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Completed Phase 3 Interventional

A Study to Evaluate Efficacy and Safety of Bitopertin in Participants With Persistent, Predominant Negative Symptoms of Schizophrenia

ClinicalTrials.gov ID: NCT01192880

Public ClinicalTrials.gov record NCT01192880. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 13, 2026, 10:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multi-Center, Randomized, 24 Week, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate Efficacy and Safety of RO4917838 in Stable Patients With Persistent, Predominant Negative Symptoms of Schizophrenia Treated With Antipsychotics Followed by a 28 Week, Double-Blind Treatment Period

Study identification

NCT ID
NCT01192880
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
625 participants

Conditions and interventions

Conditions

Interventions

  • Antipsychotics Drug
  • Bitopertin Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2010
Primary completion
Jun 30, 2014
Completion
Jun 30, 2014
Last update posted
Feb 14, 2017

2010 – 2014

United States locations

U.S. sites
27
U.S. states
14
U.S. cities
27
Facility City State ZIP Site status
Clinical Innovtions Inc Costa Mesa California 92626
Synergy Clinical Research of Escondido Escondido California 92025
San Fernando Mental Health Center Granada Hills California 91344
University of California San Diego La Jolla California 92093
Excell Research Oceanside California 92056
Artemis Institute for Clinical Research, LLC San Diego California 92103
Collaborative Neuroscience Network Inc. Torrance California 90502
Behavioral Clinical Research Inc. Lauderhill Florida 33319
University of Miami Miller School of Medicine Miami Florida 33136
Medical Research Group of Central Florida Orange City Florida 3273
Berma Research Group Plantation Florida 33317
Atlanta Center For Medical Research Atlanta Georgia 30308
Indiana University; LaRue Carter Memorial Hospital-Research Unit Indianapolis Indiana 46222
Clinical Insights, Inc. Glen Burnie Maryland 21061
Precise Research Centers Flowood Mississippi 39232
Altea Research Institute Las Vegas Nevada 89102
Ocean Rheumatology Toms River New Jersey 08775
State University of New York at Buffalo; Department of Psychiatry Buffalo New York 14215
New York State Psychiatric Institute; Psychiatry Dept of Columbia University New York New York 10032
Finger Lakes Clinical Research Rochester New York 14618
Duke University Durham North Carolina 27705
Keystone Clinical Studies, LLC Norristown Pennsylvania 19403
Scranton Medical Institutes Llc. Scranton Pennsylvania 18503
Community Clinical Research Inc. Austin Texas 78754
University Hills Clinical Research Irving Texas 75062
Lifetree Clinical Research Salt Lake City Utah 84106
Eastside Therapeutic Resource Kirkland Washington 98033

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01192880, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 14, 2017 · Synced May 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01192880 live on ClinicalTrials.gov.

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