A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis
Public ClinicalTrials.gov record NCT01194570. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicentre, Randomized, Parallel-group, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized, parallel group, double-blind, placebo controlled study will evaluate the efficacy and safety of ocrelizumab in participants with primary progressive multiple sclerosis. Eligible participants will be randomized 2 : 1 to receive either ocrelizumab or placebo.
Study identification
- NCT ID
- NCT01194570
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 735 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2, 2011 (Actual)
- Primary completion
- Jul 23, 2015 (Actual)
- Completion
- Dec 31, 2022 (Actual)
- Last update posted
- Jan 10, 2024
2011 – 2022
United States locations
- U.S. sites
- 37
- U.S. states
- 22
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Neurological Associates Ltd | Phoenix | Arizona | 85006 | — |
| Barrow Neurology Clinic | Phoenix | Arizona | 85013 | — |
| Mayo Clinic- Scottsdale | Scottsdale | Arizona | 85259 | — |
| Arizona Neuroscience Research LLC | Phoenix | Arkansas | 85032-2181 | — |
| Sutter East Bay Medical Foundation | Berkeley | California | 94705 | — |
| MS Center of Southern California | Newport Beach | California | 92663 | — |
| Univ of CA Davis Med Ctr; Neurology | Sacramento | California | 95817 | — |
| Univ of CA San Francisco; Department of Neurology | San Francisco | California | 94143 | — |
| University of Colorado; Anschutz Medical Campus Department of Neurology | Aurora | Colorado | 80045 | — |
| University of Miami School of Medicine; Dept. of Neurology Movement Disorder Center | Miami | Florida | 33136 | — |
| Vero Beach Neurology and Research Institute | Vero Beach | Florida | 32960 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| MidAmerica Neuroscience Institute | Prairie Village | Kansas | 66206 | — |
| Wayne State University; Department of Neurology | Detroit | Michigan | 48201 | — |
| Henry Ford Health System; Neurology & Neurosurgery | Detroit | Michigan | 48202 | — |
| Michigan Institute for Neurological Disorders | Farmington Hills | Michigan | 48334 | — |
| University of Minnesota; Clin. Neuro Research Unit | Minneapolis | Minnesota | 55414 | — |
| Washington University School of Medicine; Department of Neurology | St Louis | Missouri | 63110 | — |
| Holy Name Hospital | Teaneck | New Jersey | 07666 | — |
| University of New Mexico; MS Specialty Clinic | Albuquerque | New Mexico | 87131 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Weill Medical College of Cornell University; Judith Jaffe MS Ctr | New York | New York | 10021 | — |
| Mount Sinai School of Medicine; Neurology | New York | New York | 10029 | — |
| Comprehensive MS Care Center at South Shore Neurologic Assoc. | Patchogue | New York | 11772 | — |
| Neurology Assoc of Stony Brook | Stony Brook | New York | 11794 | — |
| Carolinas Medical Center; Ms Center | Charlotte | North Carolina | 28207 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607-6520 | — |
| The Ohio State University Wexner Medical Center; Department of Neurology | Columbus | Ohio | 43221 | — |
| Oklahoma Medical Research Foundation; MS Center of Excellence | Oklahoma City | Oklahoma | 73104 | — |
| Trustees of the University of Pennsylvania; Neurology | Philadelphia | Pennsylvania | 19104 | — |
| The Neurology Foundation, Inc. | Providence | Rhode Island | 02905 | — |
| Neurology Clinic PC | Cordova | Tennessee | 38018 | — |
| University of Texas Southwestern | Dallas | Texas | 75390-8897 | — |
| Maxine Mesinger MS Clinic/Baylor College of Medicine; Neurology | Houston | Texas | 77030 | — |
| Neurological Associates, Inc. | Richmond | Virginia | 23229 | — |
| Swedish Neuroscience Institute; Multiple Sclerosis Center | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 147 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01194570, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 10, 2024 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01194570 live on ClinicalTrials.gov.