ClinicalTrials.gov record
Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer
ClinicalTrials.gov ID: NCT01196429
Public ClinicalTrials.gov record NCT01196429. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Evaluation of Temsirolimus (CCI-779) (NCI Supplied Agent: NSC# 683864,) in Combination With Carboplatin and Paclitaxel Followed by Temsirolimus Consolidation as First-Line Therapy in the Treatment of Clear Cell Carcinoma of the Ovary
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial studies how well temsirolimus, carboplatin, and paclitaxel as first-line therapy works in treating patients with newly diagnosed stage III-IV clear cell ovarian cancer. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving temsirolimus with combination chemotherapy may be an effective treatment for ovarian cancer.
Study identification
- NCT ID
- NCT01196429
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 90 participants
Conditions and interventions
Interventions
- Carboplatin Drug
- Docetaxel Drug
- Laboratory Biomarker Analysis Other
- Paclitaxel Drug
- Temsirolimus Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2010 (Type not available)
- Primary completion
- Jan 2015 (Actual)
- Completion
- Jan 2015 (Actual)
- Last update posted
- Aug 8, 2019
2010 – 2015
United States locations
- U.S. sites
- 121
- U.S. states
- 28
- U.S. cities
- 85
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saint Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Los Angeles County-USC Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California | 94040 | — |
| University of Colorado Cancer Center - Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Florida Hospital Orlando | Orlando | Florida | 32803 | — |
| Memorial University Medical Center | Savannah | Georgia | 31404 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Sudarshan K Sharma MD Limted-Gynecologic Oncology | Hinsdale | Illinois | 60521 | — |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | — |
| Cadence Cancer Center in Warrenville | Warrenville | Illinois | 60555 | — |
| Elkhart Clinic | Elkhart | Indiana | 46514-2098 | — |
| Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | 46514 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Saint Vincent Oncology Center | Indianapolis | Indiana | 46260 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | 46563 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Michiana Hematology Oncology PC-South Bend | South Bend | Indiana | 46601 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| Northern Indiana Cancer Research Consortium CCOP | South Bend | Indiana | 46628 | — |
| Michiana Hematology Oncology PC-Westville | Westville | Indiana | 46391 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Iowa Oncology Research Association CCOP | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| Walter Reed Army Medical Center-Olney | Olney | Maryland | 20832 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| Michigan Cancer Research Consortium CCOP | Ann Arbor | Michigan | 48106 | — |
| Oakwood Hospital and Medical Center | Dearborn | Michigan | 48124 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Saint John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48502 | — |
| Genesys Regional Medical Center | Grand Blanc | Michigan | 48439 | — |
| Gynecologic Oncology of West Michigan PLLC | Grand Rapids | Michigan | 49546 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49001 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Sparrow Hospital | Lansing | Michigan | 48912 | — |
| Saint Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Michiana Hematology Oncology PC-Niles | Niles | Michigan | 49120 | — |
| Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341 | — |
| Saint Joseph Mercy Port Huron | Port Huron | Michigan | 48060 | — |
| Saint Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Mercy Hospital-Joplin | Joplin | Missouri | 64804 | — |
| Cancer Research for the Ozarks NCORP | Springfield | Missouri | 65804 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89169 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Summa Akron City Hospital/Cooper Cancer Center | Akron | Ohio | 44304 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | 44124 | — |
| Lake University Ireland Cancer Center | Mentor | Ohio | 44060 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Tulsa Cancer Institute | Tulsa | Oklahoma | 74146 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Geisinger Medical Center-Cancer Center Hazleton | Hazleton | Pennsylvania | 18201 | — |
| Geisinger Medical Group | State College | Pennsylvania | 16801 | — |
| Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| Women and Infants Hospital | Providence | Rhode Island | 02905 | — |
| M D Anderson Cancer Center CCOP Research Base | Houston | Texas | 77030 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| PeaceHealth Medical Group PC | Bellingham | Washington | 98226 | — |
| Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | 98310 | — |
| Harrison Medical Center | Bremerton | Washington | 98310 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Skagit Valley Hospital Regional Cancer Care Center | Mount Vernon | Washington | 98273 | — |
| Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | 98370 | — |
| Pacific Gynecology Specialists | Seattle | Washington | 98104 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
| Group Health Cooperative-Seattle | Seattle | Washington | 98112 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122-4307 | — |
| Northwest Hospital | Seattle | Washington | 98133 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Olympic Medical Cancer Care Center | Sequim | Washington | 98384 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Rockwood Cancer Treatment Center-DHEC-Downtown | Spokane | Washington | 99204 | — |
| MultiCare Tacoma General Hospital | Tacoma | Washington | 98405 | — |
| Saint Joseph Medical Center | Tacoma | Washington | 98405 | — |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| Wenatchee Valley Hospital and Clinics | Wenatchee | Washington | 98801 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01196429, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 8, 2019 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01196429 live on ClinicalTrials.gov.