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Completed Phase 3 Interventional Results available

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.

ClinicalTrials.gov ID: NCT01197521

Public ClinicalTrials.gov record NCT01197521. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

(OSKIRA-1): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Fostamatinib Disodium in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate

Study identification

NCT ID
NCT01197521
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
923 participants

Conditions and interventions

Interventions

  • fostamatinib Drug
  • placebo, fostamatinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2010
Primary completion
Oct 31, 2012
Completion
Oct 31, 2012
Last update posted
Apr 6, 2014

2010 – 2012

United States locations

U.S. sites
41
U.S. states
24
U.S. cities
41
Facility City State ZIP Site status
Research Site Anniston Alabama
Research Site Huntsville Alabama
Research Site Tuscaloosa Alabama
Research Site Tucson Arizona
Research Site Huntington Beach California
Research Site Long Beach California
Research Site Santa Maria California
Research Site Santa Monica California
Research Site Colorado Springs Colorado
Research Site Bridgeport Connecticut
Research Site Lewes Delaware
Research Site Daytona Beach Florida
Research Site Ocala Florida
Research Site Atlanta Georgia
Research Site Marietta Georgia
Research Site Idaho Falls Idaho
Research Site Springfield Illinois
Research Site Wichita Kansas
Research Site Bowling Green Kentucky
Research Site Flowood Mississippi
Research Site Florissant Missouri
Research Site Richmond Heights Missouri
Research Site St Louis Missouri
Research Site Kalispell Montana
Research Site Albuquerque New Mexico
Research Site Albany New York
Research Site Brooklyn New York
Research Site Olean New York
Research Site Asheville North Carolina
Research Site Greensboro North Carolina
Research Site Perrysburg Ohio
Research Site Lake Oswego Oregon
Research Site Erie Pennsylvania
Research Site Waxford Pennsylvania
Research Site Charleston South Carolina
Research Site Hixson Tennessee
Research Site Memphis Tennessee
Research Site Dallas Texas
Research Site Houston Texas
Research Site Mesquite Texas
Research Site San Antonio Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 86 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01197521, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 6, 2014 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01197521 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →