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Completed Phase 3 Interventional Results available

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.

ClinicalTrials.gov ID: NCT01197534

Public ClinicalTrials.gov record NCT01197534. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 7:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

(OSKIRA-2): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Fostamatinib Disodium in Rheumatoid Arthritis Patients With an Inadequate Response to DMARDs

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate the effectiveness of two dosing regimens of fostamatinib compared to placebo, in patients with rheumatoid arthritis (RA) who are taking disease modifying anti-rheumatic drug (DMARD) but not responding. The study will last for 1 year.

Study identification

NCT ID
NCT01197534
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
913 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2010
Primary completion
Feb 28, 2013
Completion
Feb 28, 2013
Last update posted
Apr 16, 2014

2010 – 2013

United States locations

U.S. sites
57
U.S. states
28
U.S. cities
57
Facility City State ZIP Site status
Research Site Birmingham Alabama
Research Site Glendale Arizona
Research Site Mesa Arizona
Research Site Phoenix Arizona
Research Site Scottsdale Arizona
Research Site Tucson Arizona
Research Site Hot Springs Arkansas
Research Site Huntington Beach California
Research Site Torrance California
Research Site Trumbull Connecticut
Research Site Washington D.C. District of Columbia
Research Site Boca Raton Florida
Research Site Brandon Florida
Research Site Jacksonville Florida
Research Site Miami Florida
Research Site Orlando Florida
Research Site Tampa Florida
Research Site Venice Florida
Research Site Zephyrhills Florida
Research Site Canton Georgia
Research Site Decatur Georgia
Research Site Macon Georgia
Research Site Boise Idaho
Research Site South Bend Indiana
Research Site Elizabethtown Kentucky
Research Site Crofton Maryland
Research Site Cumberland Maryland
Research Site Hagerstown Maryland
Research Site Kalamazoo Michigan
Research Site Flowood Mississippi
Research Site St Louis Missouri
Research Site Kalispell Montana
Research Site Omaha Nebraska
Research Site Manalapan New Jersey
Research Site Las Cruces New Mexico
Research Site Brooklyn New York
Research Site Rochester New York
Research Site Roslyn New York
Research Site Syracuse New York
Research Site Charlotte North Carolina
Research Site Durham North Carolina
Research Site Dayton Ohio
Research Site Duncansville Pennsylvania
Research Site Philadelphia Pennsylvania
Research Site West Reading Pennsylvania
Research Site Greenville South Carolina
Research Site Orangeburg South Carolina
Research Site Memphis Tennessee
Research Site Amarillo Texas
Research Site Austin Texas
Research Site Dallas Texas
Research Site Houston Texas
Research Site Lubbock Texas
Research Site Mesquite Texas
Research Site San Antonio Texas
Research Site Chesapeake Virginia
Research Site Tacoma Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 92 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01197534, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2014 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01197534 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →