Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement
Public ClinicalTrials.gov record NCT01198873. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Placebo-Controlled, Double-Blind, Randomized, Multi-center Study to Assess the Effects of Dronedarone 400 mg BID on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Objective: \- Evaluate the effect of dronedarone versus placebo (standard therapy) in slowing the progression of adverse left atrial remodeling in patients with atrial fibrillation (AF) following 12 months of treatment. Secondary Objectives: * Evaluate the effects of dronedarone versus placebo on left atrial function; * Evaluate the effects of dronedarone versus placebo on left atrial dimension; * Evaluate the effects of dronedarone versus placebo on left ventricular function (LVEF, E, E', A, E/E') * Evaluate the safety and tolerability of dronedarone.
Study identification
- NCT ID
- NCT01198873
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2010 (Type not available)
- Primary completion
- Jan 2012 (Actual)
- Completion
- Jan 2012 (Actual)
- Last update posted
- Feb 12, 2013
2010 – 2012
United States locations
- U.S. sites
- 56
- U.S. states
- 28
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 840072 | Phoenix | Arizona | 85006 | — |
| Investigational Site Number 840015 | Little Rock | Arkansas | 72204 | — |
| Investigational Site Number 840086 | Beverly Hills | California | 90211 | — |
| Investigational Site Number 840018 | Loma Linda | California | 92354 | — |
| Investigational Site Number 840029 | Merced | California | 95348 | — |
| Investigational Site Number 840044 | Redwood City | California | 94062 | — |
| Investigational Site Number 840042 | Santa Ana | California | 92704 | — |
| Investigational Site Number 840060 | Vista | California | 92083 | — |
| Investigational Site Number 840057 | Stamford | Connecticut | 06905 | — |
| Investigational Site Number 840002 | Newark | Delaware | 19713 | — |
| Investigational Site Number 840063 | Wilmington | Delaware | 19808 | — |
| Investigational Site Number 840070 | Bradenton | Florida | 34205 | — |
| Investigational Site Number 840010 | Jacksonville | Florida | 32216 | — |
| Investigational Site Number 840071 | Jupiter | Florida | 33458 | — |
| Investigational Site Number 840061 | Lakeland | Florida | 33805 | — |
| Investigational Site Number 840096 | Lauderdale Lakes | Florida | 33313 | — |
| Investigational Site Number 840031 | Ocala | Florida | 34471 | — |
| Investigational Site Number 840074 | Orlando | Florida | 32803 | — |
| Investigational Site Number 840016 | Ormond Beach | Florida | 32174 | — |
| Investigational Site Number 840051 | St. Petersburg | Florida | 33709 | — |
| Investigational Site Number 840081 | Roswell | Georgia | 30076 | — |
| Investigational Site Number 840103 | Jerseyville | Illinois | 62052 | — |
| Investigational Site Number 840106 | Peoria | Illinois | 61606 | — |
| Investigational Site Number 840066 | Elkhart | Indiana | 46514 | — |
| Investigational Site Number 840099 | Lexington | Kentucky | 40504 | — |
| Investigational Site Number 840039 | Owensboro | Kentucky | 42303 | — |
| Investigational Site Number 840092 | Baton Rouge | Louisiana | 70808 | — |
| Investigational Site Number 840040 | Auburn | Maine | 04210 | — |
| Investigational Site Number 840077 | Ayer | Massachusetts | 01432 | — |
| Investigational Site Number 840050 | Alpena | Michigan | 49707 | — |
| Investigational Site Number 840041 | Saginaw | Michigan | 48670 | — |
| Investigational Site Number 840058 | Minneapolis | Minnesota | 55422 | — |
| Investigational Site Number 840101 | Picayune | Mississippi | 39466 | — |
| Investigational Site Number 840078 | St Louis | Missouri | 63122 | — |
| Investigational Site Number 840038 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840102 | St Louis | Missouri | 63128 | — |
| Investigational Site Number 840012 | Kalispell | Montana | 59901 | — |
| Investigational Site Number 840090 | Lincoln | Nebraska | 68506 | — |
| Investigational Site Number 840045 | Buffalo | New York | 14215 | — |
| Investigational Site Number 840055 | Manhasset | New York | 11030 | — |
| Investigational Site Number 840003 | The Bronx | New York | 10468 | — |
| Investigational Site Number 840004 | Troy | New York | 12180 | — |
| Investigational Site Number 840009 | Maumee | Ohio | 43537 | — |
| Investigational Site Number 840028 | Camp Hill | Pennsylvania | 17011 | — |
| Investigational Site Number 840067 | Wyomissing | Pennsylvania | 19610 | — |
| Investigational Site Number 840027 | Wakefield | Rhode Island | 02879 | — |
| Investigational Site Number 840046 | Knoxville | Tennessee | 37917 | — |
| Investigational Site Number 840014 | Longview | Texas | 75605 | — |
| Investigational Site Number 840068 | Danville | Virginia | 24541 | — |
| Investigational Site Number 840069 | Manassas | Virginia | 20109 | — |
| Investigational Site Number 840087 | Richmond | Virginia | 23249 | — |
| Investigational Site Number 840085 | Winchester | Virginia | 22601 | — |
| Investigational Site Number 840013 | Burien | Washington | 98166 | — |
| Investigational Site Number 840091 | Spokane | Washington | 99204 | — |
| Investigational Site Number 840080 | Madison | Wisconsin | 53713 | — |
| Investigational Site Number 840023 | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01198873, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2013 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01198873 live on ClinicalTrials.gov.