A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy
Public ClinicalTrials.gov record NCT01200394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP, MULTI-CENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ONCE-DAILY ADMINISTRATION OF A PHOSPHODIESTERASE 5 INHIBITOR (PF-00489791) IN ADULTS WITH TYPE 2 DIABETES AND OVERT NEPHROPATHY
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
PF-00489791 is an inhibitor of phosphodiesterase type 5. Our hypothesis is that PF-00489791 will enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function.
Study identification
- NCT ID
- NCT01200394
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 256 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2010 (Actual)
- Primary completion
- Jul 2013 (Actual)
- Completion
- Aug 2013 (Actual)
- Last update posted
- Mar 12, 2019
2010 – 2013
United States locations
- U.S. sites
- 63
- U.S. states
- 24
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saadat Ansari Internal Medicine | Huntsville | Alabama | 35801 | — |
| The Office of Iqbal Saeed MD, LLC | Huntsville | Alabama | 35805 | — |
| AKDHC Medical Research Services, LLC* | Glendale | Arizona | 85306 | — |
| Southwest Clinical Research Institute, LLC | Tempe | Arizona | 85281 | — |
| Southwest Clinical Research Institute, LLC | Tempe | Arizona | 85284 | — |
| North America Research Institute | Azusa | California | 91702 | — |
| North American Research Institute / California Kidney Specialist | Azusa | California | 91702 | — |
| Citrus Dialysis Center | Covina | California | 91723 | — |
| California Institute of Renal Research | La Mesa | California | 91942 | — |
| Capital Nephrology Clinical Research | Sacramento | California | 95825 | — |
| California Kidney Specialists | San Dimas | California | 91773 | — |
| American Institute of Research | Whittier | California | 90602 | — |
| Whittier Internal Medicine Nephrology Medical Group | Whittier | California | 90602 | — |
| North Valley Nephrology | Yuba City | California | 95991 | — |
| Riverside Clinical Research | Edgewater | Florida | 32132 | — |
| Palm Springs Research Institute | Hialeah | Florida | 33012 | — |
| ASA Clinical Research, LLC | Jupiter | Florida | 33458 | — |
| Lakeview Medical Research | Summerfield | Florida | 34491 | — |
| Rockdale Medical Research Associates | Conyers | Georgia | 30094 | — |
| Renal Physicians of Georgia | Macon | Georgia | 31217 | — |
| Boise Kidney and Hypertension Institute | Meridian | Idaho | 83642 | — |
| Chicago Clinical Research Institute, Inc. | Chicago | Illinois | 60616 | — |
| Associates in Nephrology, SC | Evergreen Park | Illinois | 60805 | — |
| Research by Design, LLC | Evergreen Park | Illinois | 60805 | — |
| RenalCare Associates | Peoria | Illinois | 61603 | — |
| Investigative Clinical Research of Indiana, LLC | Elwood | Indiana | 46036 | — |
| Kansas Nephrology Research Institute, LLC | Wichita | Kansas | 67214 | — |
| Four Rivers Clinical Research, Inc. | Paducah | Kentucky | 42003 | — |
| Crescent City Clinical Research Center | Metairie | Louisiana | 70006 | — |
| Northwest Louisiana Nephrology | Shreveport | Louisiana | 71101 | — |
| Biolab Research, LLC | Rockville | Maryland | 20852 | — |
| Alzohaili Medical Consultants | Dearborn | Michigan | 48124 | — |
| Apex Medical Research, AMR, Inc. | Flint | Michigan | 48504 | — |
| Apex Medical Research, MI, Inc. | Flint | Michigan | 48504 | — |
| Clinical Research Consultants, LLC | Kansas City | Missouri | 64111 | — |
| Lincoln Nephrology and Hypertension | Lincoln | Nebraska | 68510 | — |
| Nebraska Nephrology Research Institute, LLC - Research Management, Inc. | Lincoln | Nebraska | 68510 | — |
| Alliance Against Diabetes | Las Vegas | Nevada | 89101 | — |
| Clinical Research Consortium | Las Vegas | Nevada | 89119 | — |
| Jacobi Medical Center - Department of Medicine - Nephrology | The Bronx | New York | 10461 | — |
| Mountain Kidney and Hypertension Associates, PA | Asheville | North Carolina | 28801 | — |
| Trial Management Associates | Wilmington | North Carolina | 28401 | — |
| Lake Medical Research | Willoughby Hills | Ohio | 44094 | — |
| Northeast Clinical Research Center, LLC | Bethlehem | Pennsylvania | 18017 | — |
| Preferred Primary Care Physicians, Inc. | Uniontown | Pennsylvania | 15401 | — |
| Columbia Nephrology Associates, PA | Columbia | South Carolina | 29203 | — |
| Carolina Nephrology, PA | Greenville | South Carolina | 29605 | — |
| Palmetto Nephrology, PA | Orangeburg | South Carolina | 29118 | — |
| South Carolina Nephrology & Hypertension Ctr, Inc | Orangeburg | South Carolina | 29118 | — |
| South Carolina Nephrology and Hypertension Center | Orangeburg | South Carolina | 29118 | — |
| Central Texas Kidney Associates | Austin | Texas | 78751 | — |
| Research Management, Inc. | Austin | Texas | 78751 | — |
| Diagnostic Clinic of Houston, PA | Houston | Texas | 77004 | — |
| Houston Nephrology Research | Houston | Texas | 77024 | — |
| Research Across America | Houston | Texas | 77054 | — |
| Renal Associates, PA | San Antonio | Texas | 78215 | — |
| San Antonio Kidney Disease Center Physicians Group, P.L.L.C. | San Antonio | Texas | 78229 | — |
| Nephrology Associates of Northern Virginia, Inc. | Fairfax | Virginia | 22033 | — |
| Nephrology Specialists, P.C. | Mechanicsville | Virginia | 23116 | — |
| Clinical Research Associates of Tidewater | Norfolk | Virginia | 23507 | — |
| Renal Remission & Hypertension Consultants, PLLC | Bremerton | Washington | 98310 | — |
| Sound Medical Research | Port Orchard | Washington | 98366 | — |
| Renal Remission and Hypertension Clinic | Silverdale | Washington | 98383 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01200394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 12, 2019 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01200394 live on ClinicalTrials.gov.