Biomarkers of Anti-TNF-α Therapy Efficacy in Rheumatoid Arthritis to Define Unresponsive Patients
Public ClinicalTrials.gov record NCT01211678. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Biomarkers of Anti-TNF-α Therapy Efficacy in Rheumatoid Arthritis to Define Unresponsive Patients (BATTER-UP)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study was to validate the ability of an 8-gene biomarker set to differentiate between participants who met or did not meet European League Against Rheumatism (EULAR) Disease Activity Score (DAS)-28 Good Response criteria after treatment with anti-Tumor Necrosis Factor (TNF) therapy for 14 weeks in approximately 200 anti-TNF-naïve participants. The secondary objectives of this study was (i) to compare the behavior of the 8-gene marker set in participants who were anti-TNF naïve versus those who began their second anti-TNF treatment , (ii) to develop, maintain, and utilize a biorepository of serum, plasma, RNA, and deoxyribonucleic acid (DNA) samples for additional experiments and analyses and (iii) to discover novel genetic (DNA) predictors of response to anti-TNF therapy.
Study identification
- NCT ID
- NCT01211678
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 301 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2010
- Primary completion
- Jun 30, 2013
- Completion
- Jun 30, 2013
- Last update posted
- Jun 8, 2014
2010 – 2013
United States locations
- U.S. sites
- 30
- U.S. states
- 19
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Murrieta | California | — | — |
| Research Site | Longmont | Colorado | — | — |
| Research Site | Lewes | Delaware | — | — |
| Research Site | Dunedin | Florida | — | — |
| Research Site | Ocala | Florida | — | — |
| Research Site | Orange Park | Florida | — | — |
| Research Site | Morton Grove | Illinois | — | — |
| Research Site | Baltimore | Maryland | — | — |
| Research Site | Plymouth | Massachusetts | — | — |
| Research Site | Las Vegas | Nevada | — | — |
| Research Site | Reno | Nevada | — | — |
| Research Site | Berkeley Heights | New Jersey | — | — |
| Research Site | Summit | New Jersey | — | — |
| Research Site | Floral Park | New York | — | — |
| Research Site | Orchard Park | New York | — | — |
| Research Site | Smithtown | New York | — | — |
| Research Site | Raleigh | North Carolina | — | — |
| Research Site | Wilmington | North Carolina | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Mayfield Village | Ohio | — | — |
| Research Site | Middleburg Heights | Ohio | — | — |
| Research Site | Edmund | Oklahoma | — | — |
| Research Site | Duncansville | Pennsylvania | — | — |
| Research Site | Mrytle Beach | South Carolina | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | San Anotnio | Texas | — | — |
| Research Site | Burke | Virginia | — | — |
| Research Site | Seattle | Washington | — | — |
| Research Site | Spokane | Washington | — | — |
| Research Site | Franklin | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01211678, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 8, 2014 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01211678 live on ClinicalTrials.gov.