PALACE 2: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis
Public ClinicalTrials.gov record NCT01212757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) in Subjects With Active Psoriatic Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis. Apremilast is proposed to improve signs and symptoms of psoriatic arthritis (tender and swollen joints, pain, physical function) in treated patients.
Study identification
- NCT ID
- NCT01212757
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 488 participants
Conditions and interventions
Conditions
Interventions
- Apremilast 20mg Drug
- Apremilast 30mg Drug
- Placebo + 20 mg Apremilast Drug
- Placebo + 30 mg Apremilast Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 27, 2010 (Actual)
- Primary completion
- Jul 26, 2012 (Actual)
- Completion
- Jan 25, 2017 (Actual)
- Last update posted
- May 6, 2020
2010 – 2017
United States locations
- U.S. sites
- 23
- U.S. states
- 15
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical and Translational Research Center of Alabama, PC | Tuscaloosa | Alabama | 35406 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| New England Research Associates, LLC | Trumbull | Connecticut | 6611 | — |
| Centre For Rheumatology, Immun. And Arthritis | Fort Lauderdale | Florida | 33334 | — |
| DMI Research | St. Petersburg | Florida | 33710 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Arthritis and Rheumatology of Georgia | Atlanta | Georgia | 30342 | — |
| Michael Bukhalo MD SC | Arlington Hts | Illinois | 60005 | — |
| Associated Internal Medical Specialist, PC | Battle Creek | Michigan | 49015 | — |
| Advanced Rheumatology | Lansing | Michigan | 48910 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Research West Incorporated | Kalispell | Montana | 59901 | — |
| University of Rochester Medical Center | Rochester | New York | 14623 | — |
| Vital Research | Greensboro | North Carolina | 27408 | — |
| Unifour Medical Research Associatets LLC | Hickory | North Carolina | 28602 | — |
| Rheumatic Disease Associates | Willow Grove | Pennsylvania | 19090 | — |
| Metroplex Clinical Research Center | Dallas | Texas | 75231 | — |
| Baylor Research Institute | Dallas | Texas | 75246-1613 | — |
| Arthritis Care and Diagnostic Center | Dallas | Texas | 75321 | — |
| Luckster Enterprises | San Antonio | Texas | 78232 | — |
| Seattle Rheumatology Associates | Seattle | Washington | 98104 | — |
| Tacoma Center for Arthritis Research, PS | Tacoma | Washington | 98405 | — |
| Rheumatology and Immunotherapy Center | Franklin | Wisconsin | 53132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01212757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2020 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01212757 live on ClinicalTrials.gov.