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Completed Phase 3 Interventional Results available

PALACE 2: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis

ClinicalTrials.gov ID: NCT01212757

Public ClinicalTrials.gov record NCT01212757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 1:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) in Subjects With Active Psoriatic Arthritis

Study identification

NCT ID
NCT01212757
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Amgen
Industry
Enrollment
488 participants

Conditions and interventions

Interventions

  • Apremilast 20mg Drug
  • Apremilast 30mg Drug
  • Placebo + 20 mg Apremilast Drug
  • Placebo + 30 mg Apremilast Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 26, 2010
Primary completion
Jul 25, 2012
Completion
Jan 24, 2017
Last update posted
May 5, 2020

2010 – 2017

United States locations

U.S. sites
23
U.S. states
15
U.S. cities
21
Facility City State ZIP Site status
Clinical and Translational Research Center of Alabama, PC Tuscaloosa Alabama 35406
Denver Arthritis Clinic Denver Colorado 80230
New England Research Associates, LLC Trumbull Connecticut 6611
Centre For Rheumatology, Immun. And Arthritis Fort Lauderdale Florida 33334
DMI Research St. Petersburg Florida 33710
University of South Florida Tampa Florida 33612
Arthritis and Rheumatology of Georgia Atlanta Georgia 30342
Michael Bukhalo MD SC Arlington Hts Illinois 60005
Associated Internal Medical Specialist, PC Battle Creek Michigan 49015
Advanced Rheumatology Lansing Michigan 48910
Mayo Clinic Rochester Minnesota 55905
Research West Incorporated Kalispell Montana 59901
University of Rochester Medical Center Rochester New York 14623
Vital Research Greensboro North Carolina 27408
Unifour Medical Research Associatets LLC Hickory North Carolina 28602
Rheumatic Disease Associates Willow Grove Pennsylvania 19090
Metroplex Clinical Research Center Dallas Texas 75231
Baylor Research Institute Dallas Texas 75246-1613
Arthritis Care and Diagnostic Center Dallas Texas 75321
Luckster Enterprises San Antonio Texas 78232
Seattle Rheumatology Associates Seattle Washington 98104
Tacoma Center for Arthritis Research, PS Tacoma Washington 98405
Rheumatology and Immunotherapy Center Franklin Wisconsin 53132

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01212757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 5, 2020 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01212757 live on ClinicalTrials.gov.

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