Efficacy and Safety of Alisporivir Alone or Combined With RBV or PEG in Chronic Hepatitis C Genotype 2 and 3 Treatment-naïve Participants
Public ClinicalTrials.gov record NCT01215643. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Multicenter, Randomized, Open Label, Parallel-group Phase IIB Study on the Efficacy and Safety of Oral Regimens of DEB025 Alone or in Combination With Ribavirin Versus Standard of Care (Peg-IFNα2a Plus Ribavirin) in Treatment-naïve Hepatitis C Genotype 2 and 3 Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is to investigate whether alisporivir (ALV; DEB025) alone or in combination with either ribavirin (RBV) or peginterferon alfa-2a (PEG) is more efficient compared to standard of care (PEG+RBV) in treatment-naïve participants with hepatitis C virus (HCV) genotype 2 and 3. In addition, triple therapy with DEB025 plus standard of care will be applied to participants not achieving rapid viral response (RVR) in the different arms.
Study identification
- NCT ID
- NCT01215643
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 340 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2010 (Type not available)
- Primary completion
- May 2012 (Actual)
- Completion
- May 2012 (Actual)
- Last update posted
- Aug 30, 2016
2010 – 2012
United States locations
- U.S. sites
- 16
- U.S. states
- 8
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scripps Clinic | La Jolla | California | 92037 | — |
| Sharp Rees-Stealy Medical Group, Inc. | San Diego | California | 92101 | — |
| Research and Education Inc. | San Diego | California | 92105 | — |
| Island View Gastroenterology Associates | Ventura | California | 93003 | — |
| Hawai Medical Center East LLC | Honolulu | Hawaii | 96817 | — |
| Cotton O'Neil Clinical Research | Topeka | Kansas | 66606 | — |
| The Office of Dr. Claudia Martorell | Springfield | Massachusetts | 01107 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0001 | — |
| Weill Cornell Medical Center | New York | New York | 10021 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| The North Texas Research Institute | Arlington | Texas | 76012 | — |
| Liver Associates of Texas | Houston | Texas | 77030 | — |
| Liver Specialist of Texas | Houston | Texas | 77030 | — |
| Alamo Medical Research | San Antonio | Texas | 78215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 57 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01215643, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 30, 2016 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01215643 live on ClinicalTrials.gov.