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Completed Phase 3 Interventional Results available

Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma

ClinicalTrials.gov ID: NCT01223027

Public ClinicalTrials.gov record NCT01223027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 7:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Randomized, Multi-center, Phase III Study to Compare the Safety and Efficacy of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma After Failure of Anti-angiogenic (VEGF-targeted and mTOR Inhibitor) Therapies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety and efficacy of Dovitinib versus sorafenib in patients with metastatic renal cell cancer.

Study identification

NCT ID
NCT01223027
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
564 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2011 (Type not available)
Primary completion
Jun 2014 (Actual)
Completion
Jun 2014 (Actual)
Last update posted
Dec 7, 2015

2011 – 2014

United States locations

U.S. sites
34
U.S. states
21
U.S. cities
29
Facility City State ZIP Site status
Highlands Oncology Group Dept of Highlands Oncology Grp Fayetteville Arkansas 72703 —
University of California San Diego - Moores Cancer Center Dept of Moores Cancer Ctr (5) La Jolla California 92093-0658 —
Cedars Sinai Medical Center Cedars Sinai Medical Ctr. (SC) Los Angeles California 90048 —
University of California at Los Angeles UCLA (4) Los Angeles California 90095 —
Stanford University Medical Center Cancer Clinical Trials Office Stanford California 94304 —
Rocky Mountain Cancer Centers RMCC Greenwood Village Colorado — —
Florida Cancer Specialists DeptofFloridaCancerSpecialists Fort Myers Florida 33901 —
University Cancer & Blood Center, LLC Athens Georgia 30607 —
Straub Clinic & Hospital Straub Honolulu Hawaii 96813 —
Moanalua Medical Center. Attn: Oncology Dept Honolulu Hawaii 96817 —
University of Kansas Cancer Center Univ of KS Kansas City Kansas 66160 —
University of Maryland Medical Center UMMC Baltimore Maryland 21201 —
Karmanos Cancer Institute Dept.of KarmanosCancerInst (5) Detroit Michigan 48201 —
University of Minnesota Medical Center - Fairview Univ of MN Minneapolis Minnesota 55455 —
Comprehensive Cancer Centers of Nevada CCC of Nevada (1) Las Vegas Nevada 89109 —
CINJ at Cooper University Hospital Cooper Voorhees Township New Jersey 08043 —
Memorial Sloan Kettering Cancer Center Dept. of MSKCC New York New York 90033 —
SUNY - Upstate Medical University Div. of Hematology-Oncology Syracuse New York 13210 —
New York Oncology Hematology, P.C. Dept. of New York Oncology. PC Troy New York 12180 —
Willamette Valley Clinical Studies Williamette Valley Cancer Eugene Oregon 97404 —
St. Luke's Hospital and Health Network St Luke's Bethlehem Pennsylvania — —
Medical University of South Carolina -Hollings Cancer Center Med Univ SC Charleston South Carolina 29425 —
Cancer Centers of the Carolinas CC of C -Eastside Greenville South Carolina 29605 —
Sarah Cannon Research Institute SC - 3 Chattanooga Tennessee 37404 —
The West Clinic Memphis Tennessee 38120 —
Vanderbilt University Medical Center SC Nashville Tennessee 37232 —
Baylor Health Care System/Sammons Cancer Center Dept. of Sammons Cancer (4) Dallas Texas 75246 —
Texas Oncology Texas Onc - Austin Dallas Texas 75251 —
Texas Oncology Texas Oncology - Houston Dallas Texas 75251 —
University of Texas Southwestern Medical Center UTSW Dallas Texas 75390-9034 —
Deke Slayton Cancer Center Deke Slayton Cancer Center (2) Webster Texas 77598 —
Utah Cancer Specialists Dept.of Utah Cancer Spec. (3) Salt Lake City Utah 84106 —
University of Virginia Health Systems Univ Virginia Charlottesville Virginia 22908-0334 —
Rockwood Clinic Spokane Location Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 165 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01223027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 7, 2015 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01223027 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →