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Completed Phase 2 Interventional Accepts healthy volunteers

Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults

ClinicalTrials.gov ID: NCT01230957

Public ClinicalTrials.gov record NCT01230957. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:53 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Safety and Immunogenicity of Different Formulations of a Clostridium Difficile Toxoid Vaccine Administered at Three Different Schedules in Adults Aged 40 to 75 Years at Risk of C. Difficile Infection

Study identification

NCT ID
NCT01230957
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Enrollment
650 participants

Conditions and interventions

Interventions

  • Clostridium difficile toxoids A and B (Low-dose with adjuvant) Biological
  • Clostridium difficile toxoids A and B (Low-dose without adjuvant) Biological
  • Clostridium difficile toxoids A and B (high-dose with adjuvant) Biological
  • Clostridium difficile toxoids A and B (high-dose without adjuvant) Biological
  • Placebo: 0.9% normal saline Biological

Biological

Eligibility (public fields only)

Age range
40 Years to 75 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2010
Primary completion
Oct 31, 2012
Completion
Feb 28, 2013
Last update posted
Jul 17, 2018

2010 – 2013

United States locations

U.S. sites
30
U.S. states
18
U.S. cities
28
Facility City State ZIP Site status
Not listed Redding California 96001
Not listed Bristol Connecticut 06010
Not listed Stamford Connecticut 06905
Not listed Clearwater Florida 33756
Not listed Coral Gables Florida 33134
Not listed Port Orange Florida 32127
Not listed St. Petersburg Florida 33709
Not listed Tampa Florida 33614
Not listed Atlanta Georgia 30342
Not listed Idaho Falls Idaho 83404
Not listed Newton Kansas 67114
Not listed Brockton Massachusetts 02301
Not listed Troy Michigan 48098
Not listed Neptune City New Jersey 07753
Not listed Binghamton New York 13901
Not listed Endwell New York 13760
Not listed Cary North Carolina 27518
Not listed Hickory North Carolina 28602
Not listed Raleigh North Carolina 27609
Not listed Centerville Ohio 45459
Not listed Pittsburgh Pennsylvania 15241
Not listed Uniontown Pennsylvania 15401
Not listed Mt. Pleasant South Carolina 29464
Not listed Bristol Tennessee 37620
Not listed Salt Lake City Utah 84093
Not listed Salt Lake City Utah 84109
Not listed Salt Lake City Utah 84124
Not listed Richmond Virginia 23294
Not listed Williamsburg Virginia 23185
Not listed Marshfield Wisconsin 54449

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01230957, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 17, 2018 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01230957 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →