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Withdrawn Phase 2 Interventional

Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity (BLOCK-ROP)

ClinicalTrials.gov ID: NCT01232777

Public ClinicalTrials.gov record NCT01232777. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether a single intravitreal (into the gel of the eye) injection of Avastin 0.625mg or 0.75mg is equivalent (non-inferior) to treatment with standard of care laser in infants with Type I pre-threshold retinopathy of prematurity (ROP) diagnosed at 30-36 weeks gestational age.

Study identification

NCT ID
NCT01232777
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 2
Lead sponsor
Vision Research Foundation
Other
Enrollment
Not listed

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
30 Weeks to 36 Weeks
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2012 (Type not available)
Primary completion
Apr 2015 (Estimated)
Completion
Jul 2018 (Estimated)
Last update posted
Oct 17, 2013

2012 – 2018

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
17
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027 —
Jules Stein Eye Institute, UCLA Los Angeles California 90095 —
Eye Insitute at Stanford Palo Alto California 94303 —
Bascon Palmer Eye Institute Miami Florida 33136 —
Emory Eye Center Atlanta Georgia 30322 —
Children's Hospital, Dept. of Ophthalmology Boston Massachusetts 02115 —
Associated Retinal Consultants/William Beaumont Hospital Royal Oak Michigan 48073 —
Insitute of Ophthalmology and Medical Science, New Jersey Medical School Newark New Jersey 07103 —
Department of Ophthalmology, Weill Cornell Medical College New York New York 10021 —
Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 —
Cleveland Clinic Cleveland Ohio 44105 —
Midwest Retina Dublin Ohio 43016 —
University Hospitals Eye Insitute, Rainbow Babies & Children's Hospital Mayfield Heights Ohio 44134 —
St. Christopher's Hospital for Children, Drexel Univ. School of Medicine Philadelphia Pennsylvania 19134 —
Austin Retina Associates Austin Texas 78705 —
Texas Children's Hospital Houston Texas 77030 —
University of Utah, Moran Eye Center Salt Lake City Utah 84132 —
Medical College of Wisconsin--Eye Insititute Milwaukee Wisconsin 53266 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01232777, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 17, 2013 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01232777 live on ClinicalTrials.gov.

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