Bosutinib For Autosomal Dominant Polycystic Kidney Disease
Public ClinicalTrials.gov record NCT01233869. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Of The Safety, Clinical Activity And Pharmacokinetics Of Bosutinib (PF-05208763) Versus Placebo In Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This purpose of this study is to determine if bosutinib reduces the rate of kidney enlargement in subjects with autosomal dominant polycystic kidney disease (ADPKD) entering the study with a total kidney volume greater than or equal to 750 cc and eGFR greater than or equal to 60 mL/min/1.73m2.
Study identification
- NCT ID
- NCT01233869
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 172 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2010 (Type not available)
- Primary completion
- Jul 2014 (Actual)
- Completion
- Aug 2014 (Actual)
- Last update posted
- Mar 11, 2016
2010 – 2014
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southwest Kidney Institute, PLC | Phoenix | Arizona | 85004 | — |
| Southwest Clinical Research Institute, LLC | Tempe | Arizona | 85284 | — |
| Southwest Kidney Institute, PLC | Tempe | Arizona | 85284 | — |
| Capital Nephrology Clinical Research | Sacramento | California | 95825 | — |
| Boise Kidney & Hypertension Institute, PLLC | Caldwell | Idaho | 83605 | — |
| Boise Kidney & Hypertension Institute, PLLC | Meridian | Idaho | 83642 | — |
| Renal Associates of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| New York University - HHC CTSI Clinical Research Center | New York | New York | 10016 | — |
| Doylestown Hospital MRI | Doylestown | Pennsylvania | 18901 | — |
| Doylestown Hospital | Doylestown | Pennsylvania | 18901 | — |
| Nephrology/Hypertension Specialists | Doylestown | Pennsylvania | 18901 | — |
| Renal Associates, PA | San Antonio | Texas | 78215 | — |
| San Antonio Kidney Disease Center Physicians Group, P.L.L.C. | San Antonio | Texas | 78229 | — |
| University of Virginia Health System - Nephrology | Charlottesville | Virginia | 22908 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| The Polyclinic | Seattle | Washington | 98104 | — |
| Renal Remission and Hypertension Clinic | Silverdale | Washington | 98383 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01233869, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2016 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01233869 live on ClinicalTrials.gov.