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Completed Phase 1 Interventional

Viral Therapy in Treating Young Patients With Relapsed or Refractory Solid Tumors

ClinicalTrials.gov ID: NCT01240538

Public ClinicalTrials.gov record NCT01240538. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 6:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Dose Escalation Study of Reolysin, a Replication Competent Reovirus, in Pediatric Patients With Relapsed or Refractory Solid Tumors

Study identification

NCT ID
NCT01240538
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
26 participants

Conditions and interventions

Interventions

  • wild-type reovirus Biological
  • cyclophosphamide Drug
  • laboratory biomarker analysis Other
  • pharmacological study Other

Biological · Drug · Other

Eligibility (public fields only)

Age range
3 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2010
Primary completion
Mar 31, 2014
Completion
Not listed
Last update posted
May 12, 2014

Started 2010

United States locations

U.S. sites
25
U.S. states
19
U.S. cities
24
Facility City State ZIP Site status
Children's Hospital of Alabama Birmingham Alabama 35233
Phoenix Childrens Hospital Phoenix Arizona 85016
Children's Hospital Los Angeles Los Angeles California 90027
Childrens Hospital of Orange County Orange California 92868-3874
University of California San Francisco Medical Center-Parnassus San Francisco California 94143
Alfred I duPont Hospital for Children Wilmington Delaware 19803
Children's National Medical Center Washington D.C. District of Columbia 20010
Nemours Children's Clinic - Jacksonville Jacksonville Florida 32207-8426
Lurie Children's Hospital-Chicago Chicago Illinois 60614
Indiana University Medical Center Indianapolis Indiana 46202
Riley Hospital for Children Indianapolis Indiana 46202
C S Mott Children's Hospital Ann Arbor Michigan 48109
University of Minnesota Medical Center-Fairview Minneapolis Minnesota 55455
Columbia University Medical Center New York New York 10032
Montefiore Medical Center The Bronx New York 10467-2490
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
St. Jude Children's Research Hospital Memphis Tennessee 38105
University of Texas Southwestern Medical Center Dallas Texas 75390
Cook Children's Medical Center Fort Worth Texas 76104
Baylor College of Medicine Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105
Midwest Children's Cancer Center Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01240538, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 12, 2014 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01240538 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →