Brain Activation During Accommodation to Painful Stimulation With FMRI

ClinicalTrials.gov ID: NCT01242540

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Official title

Brain Activation During Accommodation to Painful Stimulation With Functional Imaging of Pain

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Blood oxygen level dependant (BOLD) functional magnetic resonance imaging (FMRI) investigations of pain have provided substantial insight into the workings of the human brain. To date, however, the vast majority of studies have dealt with short painful stimulations. This work will expand the investigators knowledge of how longer stimulations are processed by comparing the activation pattern from a two minute painful stimulation with that of an 30-second painful stimulus. The investigators hypothesis that accommodation to the longer stimulation will be evident by either decreases in signal intensity in brain areas known to process pain, or by increasing activity in brain areas thought to be responsible for the modulation of painful perception.

Study identification

NCT ID: NCT01242540
Recruitment status: Completed
Study type: Observational
Phase: Not listed
Lead sponsor: University of Pittsburgh; Other
Enrollment: 15 participants

Conditions and interventions

Conditions

Pain

Interventions

Not listed

Eligibility (public fields only)

Age range: 18 Years to 50 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 2010 (Type not available)
Primary completion: Jun 2011 (Actual)
Completion: Oct 2016 (Actual)
Last update posted: Jun 26, 2017

2010 – 2016

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Pittsburgh	Pittsburgh	Pennsylvania	15213	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01242540, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 26, 2017 · Synced Nov 15, 2026