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Terminated Phase 2 Interventional Results available

Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205

ClinicalTrials.gov ID: NCT01247922

Public ClinicalTrials.gov record NCT01247922. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label Phase 2 Study of Single-agent Erlotinib for Patients With Pediatric Ependymoma Previously Treated With Oral Etoposide in Protocol OSI-774-205

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Participants that were assigned to the oral etoposide treatment arm in protocol OSI-774-205 and either progressed while on study or discontinued due to unacceptable toxicity related to etoposide were allowed to participate in this study to assess the safety profile of single-agent erlotinib in participants with recurrent or refractory pediatric ependymoma.

Study identification

NCT ID
NCT01247922
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
OSI Pharmaceuticals
Industry
Enrollment
4 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Year to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 23, 2011 (Actual)
Primary completion
Sep 13, 2012 (Actual)
Completion
Sep 13, 2012 (Actual)
Last update posted
Dec 6, 2024

2011 – 2012

United States locations

U.S. sites
11
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233 —
Children's Hospital of Orange County (CHOC) Orange California 92868 —
Packard Children's Hospital Palo Alto California 94304 —
The Children's Hospital Center for Cancer and Blood Disorders Aurora Colorado 80045 —
Children's National Medical Center -D.C. Center for Cancer and Blood Disorders Washington D.C. District of Columbia 20010 —
University of Miami Miami Florida 33136 —
Emory University Children's Healthcare of Atlanta Atlanta Georgia 30322 —
University of Minnesota - Amplatz Children's Hospital Minneapolis Minnesota 55455 —
Oregon Health & Sciences University Doernbecher Children's Hospital Portland Oregon 97124 —
Childrens Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 —
University of Wisconsin Madison Wisconsin 53705-2275 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01247922, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2024 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01247922 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →