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Terminated Phase 2 Interventional Results available

Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205

ClinicalTrials.gov ID: NCT01247922

Public ClinicalTrials.gov record NCT01247922. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 12:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label Phase 2 Study of Single-agent Erlotinib for Patients With Pediatric Ependymoma Previously Treated With Oral Etoposide in Protocol OSI-774-205

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Participants that were assigned to the oral etoposide treatment arm in protocol OSI-774-205 and either progressed while on study or discontinued due to unacceptable toxicity related to etoposide were allowed to participate in this study to assess the safety profile of single-agent erlotinib in participants with recurrent or refractory pediatric ependymoma.

Study identification

NCT ID
NCT01247922
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
OSI Pharmaceuticals
Industry
Enrollment
4 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Year to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 22, 2011
Primary completion
Sep 12, 2012
Completion
Sep 12, 2012
Last update posted
Dec 5, 2024

2011 – 2012

United States locations

U.S. sites
11
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Children's Hospital of Orange County (CHOC) Orange California 92868
Packard Children's Hospital Palo Alto California 94304
The Children's Hospital Center for Cancer and Blood Disorders Aurora Colorado 80045
Children's National Medical Center -D.C. Center for Cancer and Blood Disorders Washington D.C. District of Columbia 20010
University of Miami Miami Florida 33136
Emory University Children's Healthcare of Atlanta Atlanta Georgia 30322
University of Minnesota - Amplatz Children's Hospital Minneapolis Minnesota 55455
Oregon Health & Sciences University Doernbecher Children's Hospital Portland Oregon 97124
Childrens Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
University of Wisconsin Madison Wisconsin 53705-2275

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01247922, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 5, 2024 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01247922 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →