Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA)
Public ClinicalTrials.gov record NCT01264770. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
(OSKIRA-4): A Phase IIB, Multi-Centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy and Safety of Fostamatinib Disodium Monotherapy Compared With Adalimumab Monotherapy in Patients With Active Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate the improvements in signs and symptoms of rheumatoid arthritis (RA) for fostamatinib compared to placebo or adalimumab in patients who are Disease-Modifying anti-rheumatic drug (DMARD) naïve, DMARD intolerant or have had an inadequate response to DMARDs. The study will last for approximately six months
Study identification
- NCT ID
- NCT01264770
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 644 participants
Conditions and interventions
Conditions
Interventions
- Fostamatinib and placebo injections Drug
- Adalimumab and placebo of fostamatinib Drug
- Placebo of fostamatinib, fostamatinib, and placebo injections Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2011 (Type not available)
- Primary completion
- Oct 2012 (Actual)
- Completion
- Aug 2013 (Actual)
- Last update posted
- May 6, 2014
2011 – 2013
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | — | — |
| Research Site | Glendale | Arizona | — | — |
| Research Site | Mesa | Arizona | — | — |
| Research Site | Phoenix | Arizona | — | — |
| Research Site | Scottsdale | Arizona | — | — |
| Research Site | Huntington Beach | California | — | — |
| Research Site | Long Beach | California | — | — |
| Research Site | Colorado Springs | Colorado | — | — |
| Research Site | Bridgeport | Connecticut | — | — |
| Research Site | Daytona Beach | Florida | — | — |
| Research Site | Jacksonville | Florida | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | Ocala | Florida | — | — |
| Research Site | Palm Harbor | Florida | — | — |
| Research Site | Pinellas Park | Florida | — | — |
| Research Site | Venice | Florida | — | — |
| Research Site | Chicago | Illinois | — | — |
| Research Site | South Bend | Indiana | — | — |
| Research Site | Bowling Green | Kentucky | — | — |
| Research Site | Elizabethtown | Kentucky | — | — |
| Research Site | Oxon Hill | Maryland | — | — |
| Research Site | Kalamazoo | Michigan | — | — |
| Research Site | Richmond Heights | Missouri | — | — |
| Research Site | Kalispell | Montana | — | — |
| Research Site | Nashua | New Hampshire | — | — |
| Research Site | Albuquerque | New Mexico | — | — |
| Research Site | Las Cruces | New Mexico | — | — |
| Research Site | Brooklyn | New York | — | — |
| Research Site | Charlotte | North Carolina | — | — |
| Research Site | Perrysburg | Ohio | — | — |
| Research Site | Duncansville | Pennsylvania | — | — |
| Research Site | Greenville | South Carolina | — | — |
| Research Site | Jackson | Tennessee | — | — |
| Research Site | Knoxville | Tennessee | — | — |
| Research Site | Memphis | Tennessee | — | — |
| Research Site | Austin | Texas | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | Mesquite | Texas | — | — |
| Research Site | Plano | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 65 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01264770, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2014 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01264770 live on ClinicalTrials.gov.