Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients
Public ClinicalTrials.gov record NCT01270347. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Open-label, Randomized Trial to Evaluate the Safety and Efficacy of MP-376 Inhalation Solution (Aeroquin) vs. Tobramycin Inhalation Solution (TIS) in Stable CF Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Patients with cystic fibrosis (CF) suffer from chronic infections of the lower respiratory tract that can be caused by one or multiple bacteria, including Pseudomonas aeruginosa, which has been particularly problematic to eradicate and been implicated as the major cause of morbidity and mortality in CF patients. Aerosol delivery of antibiotics directly to the lung increases the local concentrations of antibiotic at the site of infection resulting in improved antimicrobial effects compared to systemic administration. Bacterial resistance to current aerosol antibiotic treatments indicate a need for improved therapies to treat CF patients with pulmonary infections caused by multi-drug resistant Pseudomonas aeruginosa and other bacteria. High concentrations of MP-376 delivered directly to the lung are projected to have antimicrobial effects on even the most resistant organisms.
Study identification
- NCT ID
- NCT01270347
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 282 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2011 (Type not available)
- Primary completion
- Oct 2012 (Actual)
- Completion
- Jun 2013 (Actual)
- Last update posted
- Dec 13, 2024
2011 – 2013
United States locations
- U.S. sites
- 99
- U.S. states
- 42
- U.S. cities
- 89
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mobile | Alabama | 36608 | — |
| Not listed | Anchorage | Alaska | 99508 | — |
| Not listed | Phoenix | Arizona | 85016 | — |
| Not listed | Tucson | Arizona | 85724 | — |
| Not listed | Little Rock | Arkansas | 72202 | — |
| Not listed | La Jolla | California | 92037 | — |
| Not listed | Long Beach | California | 90806 | — |
| Childrens Hospital | Los Angeles | California | 90027 | — |
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Oakland | California | 94611 | — |
| Not listed | Orange | California | 92868 | — |
| Not listed | Palo Alto | California | 94304 | — |
| Not listed | Sacramento | California | 95817 | — |
| Not listed | San Diego | California | 92103 | — |
| Not listed | San Diego | California | 92123 | — |
| Not listed | San Francisco | California | 94115 | — |
| Not listed | Aurora | Colorado | 80045 | — |
| Not listed | Denver | Colorado | 80206 | — |
| Not listed | Hartford | Connecticut | 06106 | — |
| Not listed | New Haven | Connecticut | 65020 | — |
| Not listed | Wilmington | Delaware | 19803 | — |
| Not listed | Gainesville | Florida | 32610 | — |
| Not listed | Jacksonville | Florida | 32207 | — |
| Not listed | Miami | Florida | 33136 | — |
| Not listed | Orlando | Florida | 32801 | — |
| Not listed | St. Petersburg | Florida | 33701 | — |
| Not listed | Tampa | Florida | 33606 | — |
| Not listed | Atlanta | Georgia | 30322 | — |
| Not listed | Boise | Idaho | 83712 | — |
| Not listed | Chicago | Illinois | 60614 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Glenview | Illinois | 60025 | — |
| Not listed | Niles | Illinois | 60714 | — |
| Not listed | Peoria | Illinois | 61637 | — |
| Not listed | Indianapolis | Indiana | 43202 | — |
| Not listed | Indianapolis | Indiana | 46202 | — |
| Not listed | Wichita | Kansas | 67214 | — |
| Not listed | Lexington | Kentucky | 40536 | — |
| Not listed | Louisville | Kentucky | 40202 | — |
| Not listed | Portland | Maine | 04102 | — |
| Not listed | Baltimore | Maryland | 21287 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Boston | Massachusetts | 02115 | — |
| Not listed | Worcester | Massachusetts | 01655 | — |
| Not listed | Ann Arbor | Michigan | 48109 | — |
| Not listed | Detroit | Michigan | 48201 | — |
| Not listed | Grand Rapids | Michigan | 49503 | — |
| Not listed | Minneapolis | Minnesota | 55455 | — |
| Not listed | Jackson | Mississippi | 39216 | — |
| Not listed | Columbia | Missouri | 65212 | — |
| Not listed | Kansas City | Missouri | 64108 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | Omaha | Nebraska | 68105 | — |
| Not listed | Las Vegas | Nevada | 89107 | — |
| Not listed | Lebanon | New Hampshire | 03756 | — |
| Not listed | Manchester | New Hampshire | 03104 | — |
| Not listed | Livingston | New Jersey | 07039 | — |
| Not listed | Morristown | New Jersey | 07962 | — |
| Not listed | Albuquerque | New Mexico | 87131 | — |
| Albany Medical College #2 | Albany | New York | 12208 | — |
| Not listed | Albany | New York | 12208 | — |
| Not listed | New Hyde Park | New York | 11042 | — |
| Not listed | New York | New York | 10003 | — |
| Not listed | New York | New York | 10032 | — |
| Not listed | Syracuse | New York | 13210 | — |
| Not listed | Valhalla | New York | 10595 | — |
| Not listed | Durham | North Carolina | 27710 | — |
| Not listed | Akron | Ohio | 44308 | — |
| Not listed | Cincinnati | Ohio | 45229 | — |
| Not listed | Columbus | Ohio | 43205 | — |
| Not listed | Dayton | Ohio | 45404 | — |
| Not listed | Toledo | Ohio | 43606 | — |
| Oklahoma CF Center | Oklahoma City | Oklahoma | 73104 | — |
| Not listed | Oklahoma City | Oklahoma | 73112 | — |
| Not listed | Hershey | Pennsylvania | 17033 | — |
| Not listed | Philadelphia | Pennsylvania | 19102 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Pittsburgh | Pennsylvania | 15224 | — |
| Not listed | Charleston | South Carolina | 29425 | — |
| Not listed | Columbia | South Carolina | 29203 | — |
| Not listed | Sioux Falls | South Dakota | 57117 | — |
| Not listed | Memphis | Tennessee | 38105 | — |
| Not listed | Nashville | Tennessee | 37232 | — |
| Not listed | Austin | Texas | 78723 | — |
| Not listed | Dallas | Texas | 75390 | — |
| Not listed | Fort Worth | Texas | 76104 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | San Antonio | Texas | 78212 | — |
| Not listed | Tyler | Texas | 75708 | — |
| Not listed | Salt Lake City | Utah | 84132 | — |
| Not listed | Colchester | Vermont | 05446 | — |
| Not listed | Charlottesville | Virginia | 22908 | — |
| Not listed | Norfolk | Virginia | 23507 | — |
| Not listed | Portsmouth | Virginia | 23708 | — |
| Not listed | Richmond | Virginia | 23298 | — |
| Not listed | Seattle | Washington | 98105 | — |
| Not listed | Morgantown | West Virginia | 26506 | — |
| Not listed | Milwaukee | Wisconsin | 53201 | — |
| Not listed | Milwaukee | Wisconsin | 53266 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01270347, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 13, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01270347 live on ClinicalTrials.gov.