Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respiratory Tract Symptoms Using Oral Corticosteroids.
Public ClinicalTrials.gov record NCT01272635. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Azithromycin for Preventing the Development of Upper Respiratory Tract Illness Into Lower Respiratory Tract Symptoms in Children and Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This protocol is comprised of two separate, but linked, clinical trials for treating preschool-aged children with recurrent severe episodes of wheezing. The first study (APRIL) will try to prevent wheezing illness from developing using azithromycin. If a wheezing illness does occur, the second trial (OCELOT) will try to decrease the severity of symptoms using oral corticosteroids.
Study identification
- NCT ID
- NCT01272635
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 607 participants
Conditions and interventions
Interventions
- Azithromycin Drug
- Prednisolone Drug
- Placebo Azithromycin Other
- Placebo Prednisolone Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 12 Months to 71 Months
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2011
- Primary completion
- Dec 31, 2014
- Completion
- Dec 31, 2014
- Last update posted
- Dec 27, 2016
2011 – 2015
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona College of Medicine | Tucson | Arizona | 85724 | — |
| Children's Hospital & Research Center Oakland | Oakland | California | 94609 | — |
| UCSF Benioff Children's Hospital | San Francisco | California | 94143 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital | Chicago | Illinois | 60614 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Children's Hospital Boston | Boston | Massachusetts | 02115 | — |
| St. Louis Children's Hospital | St Louis | Missouri | 63110 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| University of Wisconsin | Madison | Wisconsin | 53972 | — |
| Center for Urban Population Health | Milwaukee | Wisconsin | 53223 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01272635, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 27, 2016 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01272635 live on ClinicalTrials.gov.