Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease
Public ClinicalTrials.gov record NCT01276509. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Dose-ranging Study To Evaluate The Efficacy And Safety Of Pf-00547659 In Subjects With Crohn's Disease (Opera)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Adults with Crohn's disease that is clinically active despite conventional treatment will be eligible for this study. Patients may receive one of three doses of PF-00547659 (experimental drug) or placebo (inactive drug). Disease activity will be measured every two weeks.
Study identification
- NCT ID
- NCT01276509
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 265 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 6, 2011 (Actual)
- Primary completion
- Feb 7, 2014 (Actual)
- Completion
- Oct 9, 2015 (Actual)
- Last update posted
- Jun 3, 2021
2011 – 2015
United States locations
- U.S. sites
- 69
- U.S. states
- 21
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clopton Clinic | Jonesboro | Arkansas | 72401 | — |
| Gastroenterology Specialists of Arkansas | Jonesboro | Arkansas | 72401 | — |
| Little Rock Diagnostic Clinic, P.A. | Little Rock | Arkansas | 72205 | — |
| UCSD Medical Center-Thornton Hospital | La Jolla | California | 92037 | — |
| Community Clinical Trials | Orange | California | 92868 | — |
| Gastro Diagnostics | Orange | California | 92868 | — |
| Inland Gastroenterology Medical Associates, Inc. | Redlands | California | 92374 | — |
| BioMark Research Inc. | Whittier | California | 90603 | — |
| Clinical Research of the Rockies | Lafayette | Colorado | 80026 | — |
| Rocky Mountain Gastroenterology Associates | Thornton | Colorado | 80229 | — |
| Connecticut Clinical Research Foundation | Bristol | Connecticut | 06010 | — |
| Shands Endoscopy Center | Gainesville | Florida | 32608 | — |
| Shands Hospital at the University of Florida | Gainesville | Florida | 32610 | — |
| Shands Medical Plaza | Gainesville | Florida | 32610 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Center for Gastroenterology | Largo | Florida | 33777 | — |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| University of Miami Hospital and Clinic | Miami | Florida | 33136 | — |
| University of Miami Hospital | Miami | Florida | 33136 | — |
| University of Miami | Miami | Florida | FL 33136 | — |
| Cirtus Ambulartory Surgery Center | Orlando | Florida | 32806 | — |
| Internal Medicine Specialists | Orlando | Florida | 32806 | — |
| Heartland Medical Research (Administrative Only) | Clive | Iowa | 50325 | — |
| Iowa Digestive Disease Center | Clive | Iowa | 50325 | — |
| Iowa Endoscopy Center (Colonoscopy Only) | Clive | Iowa | 50325 | — |
| Metropolitan Gastroenterology Group, PC - Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| University of Massachusetts Worcester | Worcester | Massachusetts | 01655 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| Surgical Centers of Michigan | Troy | Michigan | 48098 | — |
| Minneapolis Heart Institute, West Health Campus | Minneapolis | Minnesota | 55404 | — |
| Noran Neurology Clinic | Minneapolis | Minnesota | 55407 | — |
| Consulting Radiology (Xray testing only) | Plymouth | Minnesota | 55446 | — |
| Minnesota Gastroenterology, P.A. | Plymouth | Minnesota | 55446 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Surgery Center of Columbia | Columbia | Missouri | 65201 | — |
| Audrain Medical Center | Mexico | Missouri | 65265 | — |
| Center for Digestive and Liver Diseases, Inc. | Mexico | Missouri | 65265 | — |
| Barnes-Jewish Hospital - Investigational Drug Services | St Louis | Missouri | 63110 | — |
| Center for Advanced Medicine | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Life Medi-Research And Management | Brooklyn | New York | 11206 | — |
| New York Hospital Queens | Flushing | New York | 11355 | — |
| Long Island Clinical Research Associates, LLP | Great Neck | New York | 11021 | — |
| Nassau Gastroenterology Associates Office Based Surgery | Great Neck | New York | 11021 | — |
| Nassau Gastroenterology Associates, P.C. | Great Neck | New York | 11021 | — |
| North Shore Primary Care, P.C. | Great Neck | New York | 11021 | — |
| Beth Israel Medical Center - Phillip Ambulatory Care Center | New York | New York | 10003 | — |
| East side Endoscopy, LLC (for colonscopy testing only) | New York | New York | 10010 | — |
| Lenox Hill Endoscopy Center | New York | New York | 10075 | — |
| Premier Medical Group of the Hudson Valley | Poughkeepsie | New York | 12601 | — |
| CTRC Hospital - UNC Memorial Hospital | Chapel Hill | North Carolina | 27514 | — |
| North Carolina Memorial Hospital Endoscopy Center | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals Department of Pharmacy | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals Endoscopy | Chapel Hill | North Carolina | 27517 | — |
| Hillsborough Campus | Hillsborough | North Carolina | 27278 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| The Offices of Dr. Vincent Armenio, M.D. | East Providence | Rhode Island | 02914 | — |
| Pharma Resource | East Providence | Rhode Island | 02915 | — |
| Bayside Endoscopy Center | Providence | Rhode Island | 02905 | — |
| Nashville Medical Research Institute | Nashville | Tennessee | 37205 | — |
| Pasadena Gastroenterology Associates, P.A. dba Digestive Health Center | Pasadena | Texas | 77505 | — |
| University of Utah HSC | Salt Lake City | Utah | 84132 | — |
| Charlottesville Gastroenterology Associates | Charlottesville | Virginia | 22902 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Allegiance Research Specialists | Wauwatosa | Wisconsin | 53226 | — |
| GI Associates | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01276509, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01276509 live on ClinicalTrials.gov.