Phase 3 Study of Dexpramipexole in ALS
Public ClinicalTrials.gov record NCT01281189. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Dexpramipexole in Subjects With Amyotrophic Lateral Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether dexpramipexole (150 mg twice daily) is safe and effective in the treatment of Amyotrophic Lateral Sclerosis (ALS).
Study identification
- NCT ID
- NCT01281189
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 942 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2011 (Type not available)
- Primary completion
- Nov 2012 (Actual)
- Completion
- Nov 2012 (Actual)
- Last update posted
- Jun 7, 2021
2011 – 2012
United States locations
- U.S. sites
- 43
- U.S. states
- 28
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute - St. Joseph's Hospital | Phoenix | Arizona | 85013 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California at San Francisco - Fresno | Fresno | California | 93701 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| University of California, Davis | Sacramento | California | 95817 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Hospital for Special Care | New Britain | Connecticut | 06053 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| University of South Florida Medical Center | Tampa | Florida | 33612 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Charlestown | Massachusetts | 02129 | — |
| St. Mary's Health Care | Grand Rapids | Michigan | 49503 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55404 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Neurology Associates, P.C. | Lincoln | Nebraska | 68506 | — |
| University of Nevada School of Medicine | Las Vegas | Nevada | 89102 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Columbia University | New York | New York | 10032 | — |
| Research Foundation of the State University of New York | Syracuse | New York | 12201 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28207 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Providence ALS Center | Portland | Oregon | 97213 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| ALS Center at Penn | Philadelphia | Pennsylvania | 19107 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19129 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Neurology | Dallas | Texas | 75214 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| University of Texas Health Sciences Center | San Antonio | Texas | 78229 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01281189, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01281189 live on ClinicalTrials.gov.