Safety and Efficacy Study of SYN115 in Parkinson's Patients Using Levodopa to Treat End of Dose Wearing Off
Public ClinicalTrials.gov record NCT01283594. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled Study of the Safety and Efficacy of SYN115 as Adjunctive Therapy in Levodopa-treated Parkinson's Subjects With End of Dose Wearing Off
Study identification
- NCT ID
- NCT01283594
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Biotie Therapies Inc.
- Industry
- Enrollment
- 420 participants
Conditions and interventions
Conditions
Interventions
- Levodopa (L-dopa) Drug
- Placebo Drug
- Tozadenant (SYN115) 120 mg BID Drug
- Tozadenant (SYN115) 180 mg BID Drug
- Tozadenant (SYN115) 240 mg BID Drug
- Tozadenant (SYN115) 60 mg BID Drug
Drug
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2011
- Primary completion
- Sep 30, 2012
- Completion
- Sep 30, 2012
- Last update posted
- Jan 16, 2019
2011 – 2012
United States locations
- U.S. sites
- 40
- U.S. states
- 24
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35005 | — |
| Not listed | La Jolla | California | 92037 | — |
| Not listed | Loma Linda | California | 92318 | — |
| Not listed | Los Angeles | California | 90001 | — |
| Not listed | Oxnard | California | 93030 | — |
| Not listed | San Francisco | California | 94016 | — |
| Not listed | Denver | Colorado | 80014 | — |
| Not listed | Manchester | Connecticut | 06040 | — |
| Not listed | New Haven | Connecticut | 06501 | — |
| Not listed | Boca Raton | Florida | 33427 | — |
| Not listed | Gainesville | Florida | 32601 | — |
| Not listed | Miami | Florida | 33101 | — |
| Not listed | Tampa | Florida | 33601 | — |
| Not listed | Weston | Florida | 33326 | — |
| Not listed | Atlanta | Georgia | 30301 | — |
| Not listed | Augusta | Georgia | 30901 | — |
| Not listed | Boise | Idaho | 83701 | — |
| Not listed | Springfield | Illinois | 62629 | — |
| Not listed | Indianapolis | Indiana | 46077 | — |
| Not listed | Des Moines | Iowa | 50047 | — |
| Not listed | Kansas City | Kansas | 66012 | — |
| Not listed | Lexington | Kentucky | 40502 | — |
| Not listed | Baltimore | Maryland | 21201 | — |
| Not listed | West Bloomfield | Michigan | 48302 | — |
| Not listed | Minneapolis | Minnesota | 55111 | — |
| Not listed | Commack | New York | 11725 | — |
| Not listed | New York | New York | 10001 | — |
| Not listed | Durham | North Carolina | 27517 | — |
| Not listed | Cincinnati | Ohio | 41073 | — |
| Not listed | Cleveland | Ohio | 44101 | — |
| Not listed | Columbus | Ohio | 43004 | — |
| Not listed | Toledo | Ohio | 43460 | — |
| Not listed | Tulsa | Oklahoma | 74008 | — |
| Not listed | Allentown | Pennsylvania | 18001 | — |
| Not listed | Philadelphia | Pennsylvania | 19019 | — |
| Not listed | Charleston | South Carolina | 29401 | — |
| Not listed | Dallas | Texas | 75001 | — |
| Not listed | Houston | Texas | 77001 | — |
| Not listed | Roanoke | Virginia | 24001 | — |
| Not listed | Milwaukee | Wisconsin | 53201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01283594, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 16, 2019 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01283594 live on ClinicalTrials.gov.