Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT01285310. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study, To Compare the Efficacy and Safety of Two Doses of Apremilast (CC-10004) in Subjects With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether Apremilast is safe and effective in the treatment of patients with rheumatoid arthritis, specifically in improving signs and symptoms of rheumatoid arthritis (tender and swollen joints, pain, physical function and structure) in treated patients who have had an inadequate response to Methotrexate.
Study identification
- NCT ID
- NCT01285310
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 237 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 9, 2010 (Actual)
- Primary completion
- Feb 21, 2012 (Actual)
- Completion
- Sep 10, 2012 (Actual)
- Last update posted
- May 8, 2020
2010 – 2012
United States locations
- U.S. sites
- 29
- U.S. states
- 14
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| ArthroCare, Arthritis Care Research | Gilbert | Arizona | 85234 | — |
| Arizona Research Center | Phoenix | Arizona | 85023 | — |
| TriWest Research Associates | La Mesa | California | 91942 | — |
| Desert Medical Advances | Palm Desert | California | 92260 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| Med Investigations/Sierra | Roseville | California | 95661 | — |
| Inland Rheumatology Clinical Trials, Inc. | Upland | California | 91786 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| In Vivo Clinical Research | Doral | Florida | 33166 | — |
| San Marcus Research Clinic | Miami | Florida | 33015 | — |
| Advanced Pharma CR, LLC | Miami | Florida | 33175 | — |
| Jeffrey Alper, MD Research | Naples | Florida | 34102 | — |
| Suncoast Clinical Research | New Port Richey | Florida | 34652 | — |
| Tampa Medical Group, PA | Tampa | Florida | 33614 | — |
| Alastair Kennedy, MD | Vero Beach | Florida | 32962 | — |
| LaPorte County Institute for Clinical Research, Inc. | Michigan City | Indiana | 46360 | — |
| Associated Internal Medicine Specialists, PC | Battle Creek | Michigan | 49015 | — |
| Saint Paul Rheumatology | Eagan | Minnesota | 55121 | — |
| Physician's East | Greenville | North Carolina | 27834 | — |
| David R. Mandel, M.D., Inc. | Mayfield | Ohio | 44143 | — |
| Health Research of Oklahoma | Oklahoma City | Oklahoma | 73103 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Austin Regional Clinic | Austin | Texas | 78759 | — |
| Metroplex Research Center | Dallas | Texas | 75231 | — |
| Modern Research Associates | Dallas | Texas | 75231 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Stone Oak Rheumatology | San Antonio | Texas | 78232 | — |
| Center for Excellence in Aging and Geriatric Health | Williamsburg | Virginia | 23185 | — |
| Arthritis Northwest, Rheumatology | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01285310, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 8, 2020 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01285310 live on ClinicalTrials.gov.