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Terminated Phase 2 Interventional Results available

Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis

ClinicalTrials.gov ID: NCT01285310

Public ClinicalTrials.gov record NCT01285310. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 7, 2026, 9:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study, To Compare the Efficacy and Safety of Two Doses of Apremilast (CC-10004) in Subjects With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate

Study identification

NCT ID
NCT01285310
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
237 participants

Conditions and interventions

Interventions

  • Apremilast 20 mg Drug
  • Apremilast 30 mg Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 8, 2010
Primary completion
Feb 20, 2012
Completion
Sep 9, 2012
Last update posted
May 7, 2020

2010 – 2012

United States locations

U.S. sites
29
U.S. states
14
U.S. cities
26
Facility City State ZIP Site status
ArthroCare, Arthritis Care Research Gilbert Arizona 85234
Arizona Research Center Phoenix Arizona 85023
TriWest Research Associates La Mesa California 91942
Desert Medical Advances Palm Desert California 92260
Stanford University Medical Center Palo Alto California 94304
Med Investigations/Sierra Roseville California 95661
Inland Rheumatology Clinical Trials, Inc. Upland California 91786
Denver Arthritis Clinic Denver Colorado 80230
In Vivo Clinical Research Doral Florida 33166
San Marcus Research Clinic Miami Florida 33015
Advanced Pharma CR, LLC Miami Florida 33175
Jeffrey Alper, MD Research Naples Florida 34102
Suncoast Clinical Research New Port Richey Florida 34652
Tampa Medical Group, PA Tampa Florida 33614
Alastair Kennedy, MD Vero Beach Florida 32962
LaPorte County Institute for Clinical Research, Inc. Michigan City Indiana 46360
Associated Internal Medicine Specialists, PC Battle Creek Michigan 49015
Saint Paul Rheumatology Eagan Minnesota 55121
Physician's East Greenville North Carolina 27834
David R. Mandel, M.D., Inc. Mayfield Ohio 44143
Health Research of Oklahoma Oklahoma City Oklahoma 73103
Altoona Center for Clinical Research Duncansville Pennsylvania 16635
Austin Regional Clinic Austin Texas 78759
Metroplex Research Center Dallas Texas 75231
Modern Research Associates Dallas Texas 75231
Sun Research Institute San Antonio Texas 78215
Stone Oak Rheumatology San Antonio Texas 78232
Center for Excellence in Aging and Geriatric Health Williamsburg Virginia 23185
Arthritis Northwest, Rheumatology Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01285310, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2020 · Synced May 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01285310 live on ClinicalTrials.gov.

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