A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.
Public ClinicalTrials.gov record NCT01288079. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIb, Randomized, Double-Blind, Placebo-Controlled, Active Controlled, Parallel Group, Multicenter Study to Assess the Safety and Efficacy of 2 Fixed Dose Groups of TC-5214 (S-mecamylamine) as Monotherapy Treatment in Patients With Major Depressive Disorder Who Exhibit an Inadequate Response to Antidepressant Therapy
Study identification
- NCT ID
- NCT01288079
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 145 participants
Conditions and interventions
Conditions
Interventions
- TC-5214 Drug
- Duloxetine Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2011
- Primary completion
- Jul 31, 2012
- Completion
- Jul 31, 2012
- Last update posted
- Nov 19, 2012
2011 – 2012
United States locations
- U.S. sites
- 25
- U.S. states
- 13
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Beverly Hills | California | — | — |
| Research Site | Chino | California | — | — |
| Research Site | Garden Grove | California | — | — |
| Research Site | San Diego | California | — | — |
| Research Site | Torrance | California | — | — |
| Research Site | Bradenton | Florida | — | — |
| Research Site | Coral Springs | Florida | — | — |
| Research Site | Jacksonville | Florida | — | — |
| Research Site | North Miami | Florida | — | — |
| Research Site | St. Petersburg | Florida | — | — |
| Research Site | West Palm Beach | Florida | — | — |
| Research Site | Atlanta | Georgia | — | — |
| Research Site | Joliet | Illinois | — | — |
| Research Site | Prairie Village | Kansas | — | — |
| Research Site | Flowood | Mississippi | — | — |
| Research Site | New York | New York | — | — |
| Research Site | Rochester | New York | — | — |
| Research Site | Dayton | Ohio | — | — |
| Research Site | Mason | Ohio | — | — |
| Research Site | Portland | Oregon | — | — |
| Research Site | Allentown | Pennsylvania | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | Seattle | Washington | — | — |
| Research Site | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01288079, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2012 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01288079 live on ClinicalTrials.gov.