Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery
Public ClinicalTrials.gov record NCT01297959. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3 Study of Efficacy and Safety of Topical E-101 Solution to Prevent Incisional Infections Among Colorectal Surgery Patients (Triple IN Study --Inhibition of Incisional Infections)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is intended to determine the efficacy, safety and tolerability of topical application of E-101 Solution directly into the surgical incisional wound in the prevention of infection of superficial and deep surgical incisional wounds. E-101 Solution is an enzyme-based antiseptic that is being developed for direct application to a surgical incision.
Study identification
- NCT ID
- NCT01297959
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 503 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2013
- Primary completion
- Oct 13, 2015
- Completion
- Oct 13, 2015
- Last update posted
- Feb 9, 2021
2013 – 2015
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Medical Center | Mobile | Alabama | 36617 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Sheridan Clinical Research, Inc. | Sunrise | Florida | 33323 | — |
| University of South Florida/Tampa General Hospital | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Stoger Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Colon & Rectal Surgery Associates | Metairie | Louisiana | 70006 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Clinic Foundation / Colon and Rectal Surgery | New Orleans | Louisiana | 70121 | — |
| Berkshire Medical Center, Inc | Pittsfield | Massachusetts | 01201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Medical IQ | Brandon | Mississippi | 39042 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Colon and Rectal Surgery, Inc. | Omaha | Nebraska | 68114 | — |
| CentraState Medical Center | Freehold | New Jersey | 07728 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Meridian Health Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Oregon Health Sciences University | Portland | Oregon | 97239 | — |
| Baylor Research Institute | Dallas | Texas | 75207 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Southwest Surgical Associates, L.L.P. | Houston | Texas | 77074 | — |
| Methodist Hospital | San Antonio | Texas | 78229 | — |
| Southwest Surgical Associates, LLP | Sugar Land | Texas | 77479 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01297959, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2021 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01297959 live on ClinicalTrials.gov.