ClinicalTrials.gov record
Opioid-induced Bowel Dysfunction (OBD) Pivotal Assessment of Lubiprostone (OPAL)
ClinicalTrials.gov ID: NCT01298219
Public ClinicalTrials.gov record NCT01298219. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-controlled, Double-blinded Study of the Efficacy and Safety of Lubiprostone in Subjects With Opioid-induced Bowel Dysfunction
Study identification
- NCT ID
- NCT01298219
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Enrollment
- 439 participants
Conditions and interventions
Conditions
Interventions
- Lubiprostone Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2010
- Primary completion
- Oct 31, 2011
- Completion
- Oct 31, 2011
- Last update posted
- Feb 10, 2020
2010 – 2011
United States locations
- U.S. sites
- 115
- U.S. states
- 32
- U.S. cities
- 92
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Alabama Research Center | Athens | Alabama | 35811 | — |
| Innovative Clinical Trials, Inc. | Birmingham | Alabama | 35205 | — |
| Achieve Clinical Research | Birmingham | Alabama | 35216 | — |
| Alabama Clinical Therapeutics | Birmingham | Alabama | 35235 | — |
| G&L Research, LLC | Foley | Alabama | 36535 | — |
| Healthscan Research | Montgomery | Alabama | 36109 | — |
| River Region Research | Tallassee | Alabama | 36078 | — |
| Anasazi Internal Medicine PC | Phoenix | Arizona | 85032 | — |
| Aureas Research, Inc | Little Rock | Arkansas | 72212 | — |
| Certified Clinical Research | Carmichael | California | 95608 | — |
| California Clinical Research, Inc. | Davis | California | 95616 | — |
| Family Medical Center | Foothill Ranch | California | 92610 | — |
| South Orange County Surgical Medical Group | Laguna Hills | California | 92653 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| Clear Vision Research | Long Beach | California | 90805 | — |
| Long Beach VA Medical Center | Long Beach | California | 90822 | — |
| Clear Vision Research | Los Angeles | California | 90023 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| North County Clinical Research | Oceanside | California | 92056 | — |
| SDS Clinical Trials, Inc. | Orange | California | 92868 | — |
| Probe Clinical Research Corporation | Riverside | California | 92501 | — |
| Probe Clinical Research Corporation - Santa Ana | Santa Ana | California | 92701 | — |
| Westlake Medical Research | Westlake Village | California | 91361 | — |
| Mountain View Clinical Research | Denver | Colorado | 80209 | — |
| Meridien Research | Bradenton | Florida | 34208 | — |
| Coastal Orthopedics & Pain Management | Bradenton | Florida | 34209 | — |
| Florida Research & Testing, LLC | Clearwater | Florida | 33755 | — |
| Avail Clinical Research | DeLand | Florida | 32720 | — |
| S&W Clinical Research | Fort Lauderdale | Florida | 33306 | — |
| Palm Springs Research Institute | Hialeah | Florida | 33012 | — |
| Kendall South Medical Center, Inc. | Miami | Florida | 33175 | — |
| Gastroenterology Group of Naples | Naples | Florida | 34102 | — |
| Physicians Regional Medical Group | Naples | Florida | 34119 | — |
| Ocala Rheumatology Research Center | Ocala | Florida | 34474 | — |
| Paddock Park Clinical Research | Ocala | Florida | 34474 | — |
| Journey Research, Inc. | Oldsmar | Florida | 34677 | — |
| Compass Research | Orlando | Florida | 32806 | — |
| Andres Patron, DO, PA | Pembroke Pines | Florida | 30026 | — |
| Advent Clinical Research Centers | Pinellas Park | Florida | 33781 | — |
| Gold Coast Research, LLC | Plantation | Florida | 33317 | — |
| Orthopedic Research Institite | Royal Palm Beach | Florida | 33411 | — |
| IC Research | Sanford | Florida | 32771 | — |
| Sarasota Memorial Pain Care Center | Sarasota | Florida | 34238 | — |
| Tampa Clinical Research | Tampa | Florida | 33624 | — |
| Southeastern Regional Research Group | Columbus | Georgia | 31904 | — |
| Better Health Clinical Research | Newnan | Georgia | 30265 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Advanced Clinical Research | Boise | Idaho | 83642 | — |
| Sonora Clinical Research | Boise | Idaho | 83702 | — |
| Nautical Clinical Research | Meridian | Idaho | 83642 | — |
| Anesthesia/Pain Control Indiana University School of Medicine | Chicago | Illinois | 60657 | — |
| Knight Center for Integrated Health | Peoria | Illinois | 61614 | — |
| Ridge Family Practice | Council Bluffs | Iowa | 51503 | — |
| Lee Research Institute | Lenexa | Kansas | 66215 | — |
| Kentucky Medical Research Center | Lexington | Kentucky | 40504 | — |
| Bluegrass Internal Medicine | Owensboro | Kentucky | 42303 | — |
| Horizon Research Group | Baton Rouge | Louisiana | 70809 | — |
| Miray Medical Center | Brockton | Massachusetts | 02301 | — |
| The Research Institute | Springfield | Massachusetts | 01107 | — |
| Coastal Research | Weymouth | Massachusetts | 02190 | — |
| Ashok Jain, MD | Dearborn | Michigan | 48124 | — |
| Shores Medical Associates | Saint Clair Shores | Michigan | 48081 | — |
| Mid-America Clinical Research LLC | St Louis | Missouri | 63139 | — |
| Montana Medical Research, Inc. | Missoula | Montana | 59808 | — |
| Independent Clinical Researchers | Las Vegas | Nevada | 89106 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Clinical Research Advantage, Inc. | Las Vegas | Nevada | 89128 | — |
| Lab2Marche | Las Vegas | Nevada | 89149 | — |
| Aloha Medical Center | Las Vegas | Nevada | 89183 | — |
| Edison Medical Group | Edison | New Jersey | 08817 | — |
| Clinical Research Program | Marlton | New Jersey | 08053 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Family Health Medical Services PLLC | Jamestown | New York | 14701 | — |
| U of Rochester | Rochester | New York | 14618 | — |
| Medical Frontiers | Carlisle | Ohio | 45005 | — |
| Hightop Medical Research Center | Cincinnati | Ohio | 45224 | — |
| Community Research | Cincinnati | Ohio | 45227 | — |
| Community Research | Cincinnati | Ohio | 45245 | — |
| Rapid Medical Research, Inc. | Cleveland | Ohio | 44122 | — |
| Parsons Avenue Medical Center | Columbus | Ohio | 43207 | — |
| Hometown Urgent Care | Groveport | Ohio | 43125 | — |
| Northstar Medical Research, LLC | Middleburg Heights | Ohio | 44130 | — |
| Pharmacotherpy Research Associates Inc | Zanesville | Ohio | 43701 | — |
| COR Clinical Research, LLC | Oklahoma City | Oklahoma | 73103 | — |
| Sooner Clinical Research | Oklahoma City | Oklahoma | 73112 | — |
| Sunstone Medical Research | Medford | Oregon | 97504 | — |
| Fanno Creek Clinic | Portland | Oregon | 97219 | — |
| McMillen & Magargle | Mechanicsburg | Pennsylvania | 17055 | — |
| Omega Medical Research | Warwick | Rhode Island | 02886 | — |
| Hartwell Research Group | Anderson | South Carolina | 29621 | — |
| Degarmo Institute of Medical Research | Greer | South Carolina | 29651 | — |
| Pain Specialists of Charleston | North Charleston | South Carolina | 29406 | — |
| Health Concepts | Rapid City | South Dakota | 57702 | — |
| InvestiClin Research | Brentwood | Tennessee | 37027 | — |
| SCRI Research Center | Germantown | Tennessee | 38138 | — |
| Prevention & Strengthening Solutions, Inc. | Humboldt | Tennessee | 38343 | — |
| FutureSearch Trials of Neurology & Sleep Lab | Austin | Texas | 78756 | — |
| Jaron Winston, MD | Austin | Texas | 78757 | — |
| KRK Medical Research | Dallas | Texas | 75230 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| Pillar Clinical Research, LLC | Dallas | Texas | 75243 | — |
| Galenos Research | Dallas | Texas | 75251 | — |
| Diversified Medical Practice, P.A. | Houston | Texas | 77027 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| Dependable Clinical Research | Houston | Texas | 77074 | — |
| Pioneer Research Solutions, Inc. | Houston | Texas | 77098 | — |
| Bobby Huynh | Richardson | Texas | 75080 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Spring Clinical Research | Sugar Land | Texas | 77478 | — |
| Pioneer Research Solutions | Sugar Land | Texas | 77479 | — |
| Lifetree Clinical Research | Salt Lake City | Utah | 84106 | — |
| ACR Research Salt Lake City | West Jordan | Utah | 84088 | — |
| Virginia Research Center, LLC | Midlothian | Virginia | 23114 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01298219, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 10, 2020 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01298219 live on ClinicalTrials.gov.