INcrease Of VAgal TonE in CHF
Public ClinicalTrials.gov record NCT01303718. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
INcrease Of VAgal TonE in CHF (INOVATE-HF) - A Randomized Study to Establish the Safety and Efficacy of CardioFit® for the Treatment of Subjects With Heart Failure and Left Ventricular Dysfunction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the INOVATE-HF study is to demonstrate the long-term safety and efficacy of vagus nerve stimulation with the CardioFit® system for the treatment of subjects with Heart Failure.
Study identification
- NCT ID
- NCT01303718
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 730 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2011 (Type not available)
- Primary completion
- Dec 2015 (Actual)
- Completion
- Dec 2015 (Actual)
- Last update posted
- Dec 15, 2015
2011 – 2015
United States locations
- U.S. sites
- 57
- U.S. states
- 27
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| Banner Research Institute | Mesa | Arizona | 85206 | — |
| Glendale Memorial Hospital | Glendale | California | 91204 | — |
| Sutter Memorial Hospital | Sacramento | California | 95819 | — |
| Chula Vista Heart Clinic | San Diego | California | 91910 | — |
| South Denver Cardiology | Denver | Colorado | 80120 | — |
| Clearwater Cardiovascular Consultants/Morton Plant | Clearwater | Florida | 33756 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Hospital, CV Research Institute | Orlando | Florida | 32803 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| St. Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Georgia Arrhythmia Consultants | Macon | Georgia | 31201 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Community Heart and Vascular Clinic | Indianapolis | Indiana | 46250 | — |
| Saint Vincent Medical Group | Indianapolis | Indiana | 46260 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Detroit Medical Center - Harper Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Detroit Clinical Research Center/Botsford Hospital | Farmington Hills | Michigan | 48334 | — |
| Michigan Cardiovascular Institute | Saginaw | Michigan | 48601 | — |
| Munson Medical Center/Traverse Heart and Vascular | Traverse | Michigan | 49684 | — |
| Park Nicollet / Methodist | Saint Louis Park | Minnesota | 55426 | — |
| United Heart & Vascular | Saint Paul | Minnesota | 55102 | — |
| Cardiology Associates of North Mississippi | Tupelo | Mississippi | 38801 | — |
| St. Luke's Mid America Heart Institute | Kansas City | Missouri | 64111 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| St. Louis Heart and Vascular | St Louis | Missouri | 63136 | — |
| Bryan Heart Institute | Lincoln | Nebraska | 68506 | — |
| Health Care Partners Cardiology/St. Rose Hospital | Las Vegas | Nevada | 89169-2579 | — |
| Mount Sinai | New York | New York | 10029 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Montefiore Medical Center/Albert Einstein Colelge of Medicine | The Bronx | New York | 10467 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267-0542 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Ohio State | Columbus | Ohio | 43210 | — |
| Oklahoma Cardiovascular Research Group | Oklahoma City | Oklahoma | 73120 | — |
| Hershey Medical Center/Penn State | Hershey | Pennsylvania | 17033 | — |
| Lancaster Heart and Stroke Foundation | Lancaster | Pennsylvania | 17602 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| VA Tennessee Valley Healthcare System | Nashville | Tennessee | 37212 | — |
| Lone Star Heart Center | Amarillo | Texas | 79106 | — |
| Texas Cardiac Arrhythmia (TCA) | Austin | Texas | 78705 | — |
| Dallas Cardiovascular Associates (CRSTI) | Dallas | Texas | 75230 | — |
| EP Heart/ETHSC at Houston | Houston | Texas | 77030 | — |
| St Lukes Episcopal | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Sentara Norfolk Hospital | Norfolk | Virginia | 23507 | — |
| Kootenai Heart Clinic | Spokane | Washington | 99204 | — |
| Multicare Health System | Tacoma | Washington | 98405 | — |
| Aurora Health Care | Lake Geneva | Wisconsin | 53147 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01303718, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 15, 2015 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01303718 live on ClinicalTrials.gov.