Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis
Public ClinicalTrials.gov record NCT01313624. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Multicenter, Randomized, Placebo-Controlled Trial Evaluating Repeated Courses of Aztreonam for Inhalation Solution in Subjects With Non-CF Bronchiectasis and Gram-Negative Endobronchial Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The AIR-BX1 study enrolled people with non-cystic fibrosis (non-CF) bronchiectasis and gram-negative airway infection. Participants received two 28-day courses of either Aztreonam for Inhalation Solution (AZLI) or placebo taken 3 times a day. Each course was followed by a 28-day off-drug period. Following the two blinded courses, all participants received a 28-day course of open-label AZLI then were followed for an additional 56 days.
Study identification
- NCT ID
- NCT01313624
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 266 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2011 (Type not available)
- Primary completion
- Mar 2013 (Actual)
- Completion
- Jun 2013 (Actual)
- Last update posted
- Apr 16, 2014
2011 – 2013
United States locations
- U.S. sites
- 36
- U.S. states
- 17
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates | Phoenix | Arizona | 85006 | — |
| Arizona Pulmonary Specialists, LTD | Phoenix | Arizona | 85012 | — |
| St. Joseph's Hospital and Medical Center Heart and Lung Institute | Phoenix | Arizona | 85013 | — |
| Arizona Pulmonary Specialists | Scottsdale | Arizona | 85258 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | — |
| UC Davis Medical Center Division of Pulmonary, Critical Care and Sleep Medicine | Sacramento | California | 95817 | — |
| Landon Pediatric Foundation | Ventura | California | 93003 | — |
| National Jewish Health | Denver | Colorado | 80202 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Bay Area Chest Physicians | Clearwater | Florida | 33756 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Pulmonary Disease Specialists (PDS) Research | Kissimmee | Florida | 34741 | — |
| University of Miami - Miller School of Medicine | Miami | Florida | 33136 | — |
| Central Florida Pulmonary Group | Orlando | Florida | 32803 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Atlanta Pulmonary Group | Atlanta | Georgia | 30342 | — |
| Pulmonary and Critical Care Associates of Baltimore | Baltimore | Maryland | 21204 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Cardio Pulmonary Research at St. Luke's Hospital | Chesterfield | Missouri | 63017 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Winthrop University Hospital - Clinical Trials Center | Mineola | New York | 11501 | — |
| St. Luke's Roosevelt Hospital | New York | New York | 10019 | — |
| University of Cincinnati / UC Health | Cincinnati | Ohio | 45267 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19102 | — |
| University of Pennsylvania Medical Center - Pulmonary, Allergy & Critical Care Division | Philadelphia | Pennsylvania | 19104 | — |
| Asthma Allergy & Pulmonary Associates | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Metroplex Pulmonary and Sleep Center | McKinney | Texas | 75069 | — |
| Alamo Clinical Research Associates | San Antonio | Texas | 78212 | — |
| University of Texas Health Science Center at Tyler | Tyler | Texas | 75708 | — |
| University of Virginia Pulmonary and Critical Care | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital/ Heart and Vascular Institute Advanced Lung Disease and Transplant Center | Falls Church | Virginia | 22042 | — |
| Swedish Medical Center/Minor James Clinic | Seattle | Washington | 98104 | — |
| Multicare Pulmonary Specialist | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01313624, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2014 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01313624 live on ClinicalTrials.gov.