Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis
Public ClinicalTrials.gov record NCT01314716. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Multicenter, Randomized, Placebo-Controlled Trial Evaluating Repeated Courses of Aztreonam for Inhalation Solution/Aztreonam 75 mg Powder and Solvent for Nebuliser Solution in Subjects With Non-CF Bronchiectasis and Gram-Negative Endobronchial Infection (AIR-BX2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The AIR-BX2 study enrolled people with non-cystic fibrosis (non-CF) bronchiectasis and gram-negative airway infection. Participants received two 28-day courses of either Aztreonam for Inhalation Solution (AZLI) or placebo taken 3 times a day. Each course was followed by a 28-day off-drug period. Following the two blinded courses, all participants received a 28-day course of open-label AZLI then were followed for an additional 56 days.
Study identification
- NCT ID
- NCT01314716
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 274 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2011 (Type not available)
- Primary completion
- Apr 2013 (Actual)
- Completion
- Jul 2013 (Actual)
- Last update posted
- Apr 16, 2014
2011 – 2013
United States locations
- U.S. sites
- 33
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Florence Research Associates | Florence | Alabama | 35630 | — |
| Clinical Trials Connection | Flagstaff | Arizona | 86001 | — |
| Phoenix Medical Group | Peoria | Arizona | 85381 | — |
| Pulmonary Associates | Phoenix | Arizona | 85006 | — |
| AZ Pulmonary Specialists, LTD | Scottsdale | Arizona | 85258 | — |
| Pulmonary Consultants & Primary Care Physicians Medical Group, Inc. | Orange | California | 92780 | — |
| UC San Diego Medical Center | San Diego | California | 92103 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| University of Florida | Jacksonville | Florida | 32209 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| Central Florida Pulmonary Group | Orlando | Florida | 32803 | — |
| Sarasota Memorial Hospital - Clinical Research Center | Sarasota | Florida | 34239 | — |
| Pasadena Center for Medical Research | St. Petersburg | Florida | 33707 | — |
| Tampa General Hospital - New Lung Associates | Tampa | Florida | 33606 | — |
| Florida Premier Research Institute | Winter Park | Florida | 32789 | — |
| Southeastern Lung Care PC | Decatur | Georgia | 30033 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Loess Hills Clinical Research | Council Bluffs | Iowa | 51503 | — |
| Kentuckiana Pulmonary Associates | Louisville | Kentucky | 40202 | — |
| Pulmonary & Critical Care Associates of Baltimore | Rosedale | Maryland | 21237 | — |
| Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08903 | — |
| Pulmonary & Allergy Associates, P.A. | Summit | New Jersey | 07901 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Columbia University, NY Presbyterian Hospital | New York | New York | 10032 | — |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| The Oregon Clinic P.C./ Pulmonary Division | Portland | Oregon | 97220 | — |
| University of Pennsylvania Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Texas Health Science Center at Tyler | Tyler | Texas | 75708 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Pulmonary Consultants, PLLC | Tacoma | Washington | 98405 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| Medical College of Wisconsin Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01314716, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2014 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01314716 live on ClinicalTrials.gov.