Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
Public ClinicalTrials.gov record NCT01324232. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Double-blind, Randomized, Placebo-controlled, Four-arm, Multicenter, Dose-finding Study to Assess the Safety and Efficacy of Three Dose Levels of AVP-923 (Dextromethorphan/Quinidine) in the Treatment of Central Neuropathic Pain in Patients With Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objectives of the study are to evaluate the safety, tolerability, and efficacy of 3 doses of AVP-923 capsules in the treatment of central neuropathic pain in participants with multiple sclerosis.
Study identification
- NCT ID
- NCT01324232
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 209 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 8, 2011 (Actual)
- Primary completion
- Sep 26, 2013 (Actual)
- Completion
- Sep 26, 2013 (Actual)
- Last update posted
- Nov 22, 2021
2011 – 2013
United States locations
- U.S. sites
- 44
- U.S. states
- 24
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Central Neurology Associates PC | Cullman | Alabama | 35058 | — |
| St. Joseph's Hospital Medical Center | Phoenix | Arizona | 85013 | — |
| Alta Bates Summit Medical Center | Berkeley | California | 94705 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| Coordinated Clinical Research | San Diego | California | 92103 | — |
| University of California, San Francisco | San Francisco | California | 94158 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Neurology Associates, PA | Maitland | Florida | 32751 | — |
| Collier Neurologic Specialists | Naples | Florida | 34102 | — |
| Laszlo J. Mate, MD | North Palm Beach | Florida | 33408 | — |
| Neurology Associates of Ormond Beach | Ormond Beach | Florida | 32174 | — |
| Neurological Associates | Pompano Beach | Florida | 33060 | — |
| Neurologique Foundation | Ponte Vedra Beach | Florida | 32082-4040 | — |
| Suncoast Neuroscience Associates, Inc. | St. Petersburg | Florida | 33713 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Geodyssey Research, LLC | Vero Beach | Florida | 32960 | — |
| Shepard Center | Atlanta | Georgia | 30309 | — |
| Rush-Presbyterian St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Consultants in Neurology | Northbrook | Illinois | 60062 | — |
| Josephson Wallack Munshower Neurology, P.C. | Indianapolis | Indiana | 46256 | — |
| MidAmerica Neuroscience Institute | Lenexa | Kansas | 66214 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Michigan Neurology Associates, P.C. | Clinton Township | Michigan | 48035 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Advanced Neurology Specialists | Great Falls | Montana | 59405 | — |
| Neurology Associates PC | Lincoln | Nebraska | 68506 | — |
| Albany Medical Center Hospital | Albany | New York | 12208 | — |
| NYU-Hospital for Joint Diseases | New York | New York | 10003 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| SUNY at Stony Brook | Stony Brook | New York | 11794 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28207 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oklahoma Medical Research Foundation | Oklahoma City | Oklahoma | 73104 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19107 | — |
| Geisinger Health System | Wilkes-Barre | Pennsylvania | 18711 | — |
| Advanced Neurosciences Institute | Franklin | Tennessee | 37064 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Rocky Mountain MS Clinic | Salt Lake City | Utah | 84103 | — |
| Neurological Associates | Henrico | Virginia | 23226 | — |
| MS Center of Greater Washington | Vienna | Virginia | 22182 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| MultiCare Health System | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01324232, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 22, 2021 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01324232 live on ClinicalTrials.gov.