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Completed Phase 1Phase 2 Interventional Results available

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

ClinicalTrials.gov ID: NCT01325207

Public ClinicalTrials.gov record NCT01325207. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 9:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I/II Dose Escalation Trial to Assess Safety of Intrathecal Trastuzumab for the Treatment of Leptomeningeal Metastases in HER2 Positive Breast Cancer

Study identification

NCT ID
NCT01325207
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Northwestern University
Other
Enrollment
34 participants

Conditions and interventions

Conditions

Interventions

  • Trastuzumab Radiation

Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2011
Primary completion
Jun 19, 2016
Completion
Jan 19, 2019
Last update posted
Sep 25, 2019

2011 – 2019

United States locations

U.S. sites
8
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
University of California San Francisco (UCSF) San Francisco California 94143-1710
Northwestern University Chicago Illinois 60611
Tufts Medical Center Boston Massachusetts 02111
Dana Farber Cancer Institute Boston Massachusetts 02215
Columbia University New York New York 10032
Memorial Sloan-Kettering Cancer Center New York New York 10065
Rhode Island Hospital Providence Rhode Island 02903
Texas Oncology-Austin Austin Texas 78705

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01325207, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2019 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01325207 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →