An Efficacy and Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting
Public ClinicalTrials.gov record NCT01339260. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Multicenter, Randomized, Double-blind, Double-dummy, Active-controlled, Parallel Group Study of the Efficacy and Safety of Oral Netupitant Administered in Combination With Palonosetron and Dexamethasone Compared to Oral Palonosetron and Dexamethasone for the Prevention of Nausea and Vomiting in Cancer Patients Receiving Moderately Emetogenic Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
NETU-08-18 is a two-arm clinical study assessing efficacy and safety of a single oral dose of netupitant and palonosetron, two antiemetic drugs, versus oral palonosetron, both given with oral dexamethasone. The objective of the study is to demonstrate that netupitant and palonosetron are more effective than palonosetron alone, to prevent nausea and vomiting induced by moderately emetogenic cancer chemotherapy after administration of repeated cycles of chemotherapy.
Study identification
- NCT ID
- NCT01339260
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,455 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2011 (Type not available)
- Primary completion
- Nov 2012 (Actual)
- Completion
- Not listed
- Last update posted
- Nov 26, 2014
Started 2011
United States locations
- U.S. sites
- 28
- U.S. states
- 16
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anniston Oncology/Regional Medical Center | Anniston | Alabama | 36207 | — |
| Northwest Alabama Cancer Center | Muscle Shoals | Alabama | 35661 | — |
| Genesis Cancer Centre | Hot Springs | Arkansas | 71913 | — |
| Compassionate Cancer Care Medical Group Inc | Corona | California | 92879 | — |
| Compassionate Cancer Centre Medical Group | Fountain Valley | California | 92708 | — |
| American Institute of Research | Los Angeles | California | 90017 | — |
| Facey Medical Group | Mission Hills | California | 91345 | — |
| Compassionate Cancer Care Medical Group | Riverside | California | 92501 | — |
| American Institute of Research | Whittier | California | 90603 | — |
| Denver Health and Hospital Authority | Denver | Colorado | 80204 | — |
| Palm Beach Institute of Hematology and Oncology | Boynton Beach | Florida | 33435 | — |
| Baptist Cancer Institute | Jacksonville | Florida | 32207 | — |
| Deaconess Clinic Downtown | Evansville | Indiana | 47713 | — |
| Floyd Memorial Cancer Center of Indiana | New Albany | Indiana | 47150 | — |
| Kentucky Cancer Clinic | Hazard | Kentucky | 41701 | — |
| The John R Marsh Cancer Center | Hagerstown | Maryland | 21742 | — |
| Fallon Clinic at Worcester Medical Center | Worcester | Massachusetts | 01608 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Piedmont Hematology Oncology Associates PA | Winston-Salem | North Carolina | 27103 | — |
| Tri-County Hematology and Oncolgy Associates Inc. | Massillon | Ohio | 44646 | — |
| Signal Point Clinical Research Center LLC | Middletown | Ohio | 45042 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| Charleston Hematology Oncology | Charleston | South Carolina | 29414 | — |
| Wellmont Medical Associates-Oncology and Hematology | Bristol | Tennessee | 37620 | — |
| Cancer Specialists of South Texas, P.A. | Corpus Christi | Texas | 78412 | — |
| The University of Texas Health Center | Tyler | Texas | 75708 | — |
| Northern Utah Associates Hematology / Oncology | Ogden | Utah | 84403 | — |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 144 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01339260, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 26, 2014 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01339260 live on ClinicalTrials.gov.