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Terminated Phase 3 Interventional Results available

LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

ClinicalTrials.gov ID: NCT01345669

Public ClinicalTrials.gov record NCT01345669. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double-blind, Placebo-controlled, Phase III Study to Evaluate the Efficacy and Safety of Afatinib (BIBW 2992) as Adjuvant Therapy After Chemo-radiotherapy in Primary Unresected Patients With Stage III, IVa, or IVb Loco-regionally Advanced Head and Neck Squamous Cell Carcinoma

Study identification

NCT ID
NCT01345669
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
617 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Afatinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 16, 2011
Primary completion
Sep 11, 2016
Completion
Sep 11, 2016
Last update posted
Dec 6, 2017

2011 – 2016

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
1200.131.00171 Boehringer Ingelheim Investigational Site Little Rock Arkansas
1200.131.00181 Boehringer Ingelheim Investigational Site Orange California
1200.131.00177 Boehringer Ingelheim Investigational Site Aurora Colorado
1200.131.00185 Boehringer Ingelheim Investigational Site New Haven Connecticut
1200.131.00173 Boehringer Ingelheim Investigational Site Baltimore Maryland
1200.131.00176 Boehringer Ingelheim Investigational Site Boston Massachusetts
1200.131.00182 Boehringer Ingelheim Investigational Site Omaha Nebraska
1200.131.00175 Boehringer Ingelheim Investigational Site Lebanon New Hampshire
1200.131.00179 Boehringer Ingelheim Investigational Site Stony Brook New York
1200.131.00188 Boehringer Ingelheim Investigational Site The Bronx New York
1200.131.10200 Boehringer Ingelheim Investigational Site Winston-Salem North Carolina
1200.131.00172 Boehringer Ingelheim Investigational Site Philadelphia Pennsylvania
1200.131.00184 Boehringer Ingelheim Investigational Site San Antonio Texas
1200.131.00198 Boehringer Ingelheim Investigational Site Spokane Valley Washington
1200.131.00183 Boehringer Ingelheim Investigational Site Wenatchee Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 147 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01345669, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2017 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01345669 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →