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Completed Phase 1Phase 2 Interventional Results available

Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)

ClinicalTrials.gov ID: NCT01349049

Public ClinicalTrials.gov record NCT01349049. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Safety and Efficacy Study of Orally Administered PLX3397 in Adults With Relapsed or Refractory FLT3-ITD Positive Acute Myeloid Leukemia (AML)

Study identification

NCT ID
NCT01349049
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Daiichi Sankyo
Industry
Enrollment
90 participants

Conditions and interventions

Interventions

  • PLX3397 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 20, 2011
Primary completion
Jan 19, 2015
Completion
Jan 8, 2018
Last update posted
Mar 1, 2020

2011 – 2018

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
UCSF Helen Diller Family Family Comprehensive Cancer Center San Francisco California 94143
Northwestern University Chicago Illinois 60611
Johns Hopkins University Baltimore Maryland 21231
Dana Farber Cancer Institute Boston Massachusetts 02215
Roswell Park Cancer Institute Buffalo New York 14263
Memorial Sloan Kettering Cancer Center New York New York 10022
New York Presby Hospital, Weill Medical College at Cornell University New York New York 10065
University of Pennsylvania, Abramson Cancer Center Philadelphia Pennsylvania 19104
Fred Hutchinson Cancer Research Center Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01349049, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 1, 2020 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01349049 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →