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Completed Phase 2 Interventional Results available

BMS-936558 (MDX-1106) In Subjects With Advanced/Metastatic Clear-Cell Renal Cell Carcinoma (RCC)

ClinicalTrials.gov ID: NCT01354431

Public ClinicalTrials.gov record NCT01354431. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 8:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Blinded, Phase 2 Dose-Ranging Study Of BMS-936558 (MDX-1106) In Subjects With Progressive, Advanced/Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to measure how active BMS-936558 (nivolumab) is against Renal Cell Carcinoma (RCC) as measured by the disease not progressing and whether a dose response relationship exists.

Study identification

NCT ID
NCT01354431
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
168 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2011 (Actual)
Primary completion
May 15, 2013 (Actual)
Completion
Apr 15, 2021 (Actual)
Last update posted
May 12, 2022

2011 – 2021

United States locations

U.S. sites
34
U.S. states
20
U.S. cities
26
Facility City State ZIP Site status
UCSD Moores Cancer Center La Jolla California 92093 —
Ucla Los Angeles California 90024 —
Samuel Oschin Comprehensive Cancer Inst. Los Angeles California 90048 —
Stanford Cancer Center Stanford California 94305 —
University Of Colorado Aurora Colorado 80045 —
Georgetown University Medical Center Washington D.C. District of Columbia 20007 —
Northwestern University Feinberg School Of Medicine Chicago Illinois 60611 —
Loyola University Medical Center Maywood Illinois 60153 —
Indiana University Health Melvin And Bren Simon Cancer Center Indianapolis Indiana 46202 —
University Of Kansas Medical Center Kansas City Kansas 66160 —
University Of Maryland Baltimore Maryland 21201 —
The Bunting-Blaustein Cancer Research Building Baltimore Maryland 21287 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Beth Israel Deaconess Medical Ctr. Boston Massachusetts 02215 —
University Of Michigan Medical Center Ann Arbor Michigan 48109 —
Wayne State University Detroit Michigan 48201 —
Masonic Cancer Ctr, University Of Minnesota Minneapolis Minnesota 55455 —
North Mississippi Hematology And Oncology Associates, Ltd Tupelo Mississippi 38801 —
Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756 —
Roswell Park Cancer Institute Buffalo New York 14263 —
St. Luke'S Roosevelt Hospital Center New York New York 10019 —
Mount Sinai Medical Center New York New York 10029 —
Memorial Sloan Kettering Nassau New York New York 10065 —
Weill Cornell Medical College New York New York 10065 —
Blumenthal Cancer Center Charlotte North Carolina 28204 —
Duke University Medical Center Durham North Carolina 27710 —
Cleveland Clinic Cleveland Ohio 44195 —
University Of Pennsylvania Philadelphia Pennsylvania 19104 —
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 —
Medical University Of South Carolina Charleston South Carolina 29425 —
Tennessee Oncology, PLLC Nashville Tennessee 37203 —
Vanderbilt-Ingram Cancer Ctr Nashville Tennessee 37232 —
University of Washington - Seattle Cancer Care Alliance Seattle Washington 98109 —
Wheaton Franciscan Health Care Wauwatosa Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01354431, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 12, 2022 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01354431 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →