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Completed Phase 3 Interventional Results available

Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial

ClinicalTrials.gov ID: NCT01369069

Public ClinicalTrials.gov record NCT01369069. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 8:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT01369069
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
University of Virginia
Other
Enrollment
1,151 participants

Conditions and interventions

Interventions

  • IV insulin to maintain target glucose concentration of 80-130 mg/dL Drug
  • Standard Care control - sliding scale insulin to keep glucose less than 180 mg/dL Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2012
Primary completion
Nov 18, 2018
Completion
Nov 18, 2018
Last update posted
Dec 22, 2019

2012 – 2018

United States locations

U.S. sites
70
U.S. states
24
U.S. cities
48
Facility City State ZIP Site status
University of Arizona Medical Center - South Campus Tucson Arizona 85713
University of Arizona Tucson Arizona 85724
Long Beach Memorial Medical Center Long Beach California 90806
Ronald Regan Medical Center Los Angeles California 90095
San Francisco General Hospital San Francisco California 94110
California Pacific Medical Center - Davies Campus San Francisco California 94114
California Pacific Medical Center-Pacific Campus San Francisco California 94114
UCSF Medical Center San Francisco California 94117
Stanford University Medical Center Stanford California 94305
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010
Mayo Clinic Jacksonville Jacksonville Florida 32224
Jackson Memorial Hospital Miami Florida 33136
Emory University Hospital - Midtown Atlanta Georgia 30308
Emory University Hospital Atlanta Georgia 30322
Grady Memorial Hospital Atlanta Georgia 30322
Augusta University Medical Center Augusta Georgia 30912
Northwestern Memorial Hospital Chicago Illinois 60611
OSF Saint Francis Medical Center Peoria Illinois 61637
University of Iowa Hospitals & Clinics Iowa City Iowa 52242
University of Kansas Medical Center Kansas City Kansas 66160
University of Kentucky Lexington Kentucky 40506
University of Maryland Medical Center Baltimore Maryland 21201
Tufts Medical Center Boston Massachusetts 02111
Massachusetts General Hospital Boston Massachusetts 02114
University of Michigan Ann Arbor Michigan 48109
Detroit Receiving Hospital Detroit Michigan 48201
Henry Ford Health System Detroit Michigan 48202
Sinai-Grace Hospital Detroit Michigan 48235
William Beaumont Hospital-Royal Oak Royal Oak Michigan 48073
William Beaumont Hospital-Troy Troy Michigan 48085
Hennepin County Medical Center Minneapolis Minnesota 55415
University of Minnesota Medical Center, Fairview Minneapolis Minnesota 55455
JFK Medical Center Edison New Jersey 08818
Hackensack University Medical Center Hackensack New Jersey 07601
Kings County Hospital Brooklyn New York 11203
SUNY Downstate University Hospital of Brooklyn Brooklyn New York 11203
Buffalo General Medical Center Buffalo New York 14210
The Mount Sinai Medical Center New York New York 10029
Columbia University Medical Center New York New York 10032
Weill Cornell Medical Center New York New York 10065
Maimonides Medical Center New York New York 11219
Lincoln Medical and Mental Health Center The Bronx New York 10451
Summa Akron City Hospital Akron Ohio 44307
University of Cincinnati Cincinnati Ohio 45221
Wexner Medical Center Columbus Ohio 43210
Miami Valley Hospital Dayton Ohio 45409
Abington Memorial Hospital Abington Pennsylvania 19001
Penn State Hershey Medical Center Hershey Pennsylvania 17033
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19102
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104
Temple University Hospital Philadelphia Pennsylvania 19140
Allegheny General Hospital Pittsburgh Pennsylvania 15212
UPMC Presbyterian Pittsburgh Pennsylvania 15213
UPMC - Mercy Pittsburgh Pennsylvania 15219
WellSpan York Hospital York Pennsylvania 17403
St. Thomas Neuroscience Research Institute Nashville Tennessee 37205
Vanderbilt University Medical Center Nashville Tennessee 37232
Dell Seton Medical Center at UT Austin Texas 78701
Seton Medical Center Austin Texas 78705
UT Southwestern-Parkland Memorial Hospital Dallas Texas 75390
UT Southwestern-Zale Lipshy University Hospital Dallas Texas 75390
Valley Baptist Medical Center Harlingen Texas 78552
Baylor College of Medicine Houston Texas 77030
Memorial Herman Hospital Houston Texas 77030
University of Utah Salt Lake City Utah 84132
University of Virginia Charlottesville Virginia 22908
Virginia Commonwealth University Richmond Virginia 23298
Harborview Medical Center Seattle Washington 98104
West Virginia University Morgantown West Virginia 26506
Froedtert Memorial Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01369069, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 22, 2019 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01369069 live on ClinicalTrials.gov.

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