Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
Public ClinicalTrials.gov record NCT01369069. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial is a multicenter, randomized, controlled clinical trial of 1400 patients that will include approximately 60 enrolling sites. The study hypotheses are that treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL - 130 mg/dL) will be safe and result in improved 3 month outcome after stroke.
Study identification
- NCT ID
- NCT01369069
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,151 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2012 (Actual)
- Primary completion
- Nov 19, 2018 (Actual)
- Completion
- Nov 19, 2018 (Actual)
- Last update posted
- Dec 23, 2019
2012 – 2018
United States locations
- U.S. sites
- 70
- U.S. states
- 24
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona Medical Center - South Campus | Tucson | Arizona | 85713 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Ronald Regan Medical Center | Los Angeles | California | 90095 | — |
| San Francisco General Hospital | San Francisco | California | 94110 | — |
| California Pacific Medical Center - Davies Campus | San Francisco | California | 94114 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94114 | — |
| UCSF Medical Center | San Francisco | California | 94117 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Emory University Hospital - Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30322 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40506 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Detroit Receiving Hospital | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Sinai-Grace Hospital | Detroit | Michigan | 48235 | — |
| William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | 48073 | — |
| William Beaumont Hospital-Troy | Troy | Michigan | 48085 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| University of Minnesota Medical Center, Fairview | Minneapolis | Minnesota | 55455 | — |
| JFK Medical Center | Edison | New Jersey | 08818 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Kings County Hospital | Brooklyn | New York | 11203 | — |
| SUNY Downstate University Hospital of Brooklyn | Brooklyn | New York | 11203 | — |
| Buffalo General Medical Center | Buffalo | New York | 14210 | — |
| The Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Weill Cornell Medical Center | New York | New York | 10065 | — |
| Maimonides Medical Center | New York | New York | 11219 | — |
| Lincoln Medical and Mental Health Center | The Bronx | New York | 10451 | — |
| Summa Akron City Hospital | Akron | Ohio | 44307 | — |
| University of Cincinnati | Cincinnati | Ohio | 45221 | — |
| Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19102 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC - Mercy | Pittsburgh | Pennsylvania | 15219 | — |
| WellSpan York Hospital | York | Pennsylvania | 17403 | — |
| St. Thomas Neuroscience Research Institute | Nashville | Tennessee | 37205 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Dell Seton Medical Center at UT | Austin | Texas | 78701 | — |
| Seton Medical Center | Austin | Texas | 78705 | — |
| UT Southwestern-Parkland Memorial Hospital | Dallas | Texas | 75390 | — |
| UT Southwestern-Zale Lipshy University Hospital | Dallas | Texas | 75390 | — |
| Valley Baptist Medical Center | Harlingen | Texas | 78552 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Memorial Herman Hospital | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Froedtert Memorial Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01369069, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 23, 2019 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01369069 live on ClinicalTrials.gov.