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Completed Phase 3 Interventional Results available

Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder

ClinicalTrials.gov ID: NCT01370733

Public ClinicalTrials.gov record NCT01370733. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:49 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Low Emission NeoSync EEG Synchronized TMS Technology for the Treatment of Major Depressive Disorder: A Multicenter, Randomized, Double-Blind, Sham-Controlled, Trial

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is designed to evaluate the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) using the NeoSync EEG Synchronized TMS device (NEST) in subjects with Major Depressive Disorder. This is a multicenter study in which subjects will be randomized to receive treatment 5 days per week for 6 weeks. Subjects who complete 6 weeks of double-blind treatment may be eligible to receive up to four weeks of open label sTMS therapy or antidepressant medications during the follow-up phase of the study. Follow-up evaluation visits will be conducted during those four weeks, with the frequency of the visits determined by the treatment choice during that timeframe.

Study identification

NCT ID
NCT01370733
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Wave Neuroscience
Industry
Enrollment
202 participants

Conditions and interventions

Eligibility (public fields only)

Age range
22 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2012
Primary completion
Jul 31, 2013
Completion
Aug 31, 2013
Last update posted
Oct 25, 2015

2012 – 2013

United States locations

U.S. sites
18
U.S. states
13
U.S. cities
18
Facility City State ZIP Site status
UCLA Depression Research & Clinic Program Los Angeles California 90024
UCSD Medical Center San Diego California 92103
UCLA-Harbor Torrance California 90509
Hartford Hospital Institute of Living Hartford Connecticut 06106
TMS Specialists Chicago Chicago Illinois 60602
Sheppard Pratt Health System Baltimore Maryland 21285
Washington University School of Medicine St Louis Missouri 63110
University of Nebraska Medical Center Omaha Nebraska 68198
Center for Mood Disorders and Neuromodulation Therapies, UMDNJ-SOM Cherry Hill New Jersey 08003
Mount Sinai School of Medicine New York New York 10029
Duke University Brain Stimulation and Neurophysiology Center Durham North Carolina 27710
Wake Forest University Medical Center Winston-Salem North Carolina 27157
University of Pennsylvania Philadelphia Pennsylvania 19104
Mood Disorders Treatment Research Program University of Pittsburgh-Western Psychiatric Institute and Clinic Pittsburgh Pennsylvania 15213
Butler Hospital Mood Disorders Research Program, Brown Department of Psychiatry and Human Behavior Providence Rhode Island 02906
MUSC Institute of Psychiatry, Brain Stimulation Lab Charleston South Carolina 29425
UT Southwestern Medical Center Dallas Texas 75390
R/D Clinical Research Lake Jackson Texas 77566

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01370733, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 25, 2015 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01370733 live on ClinicalTrials.gov.

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