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Completed Phase 2 Interventional Results available

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

ClinicalTrials.gov ID: NCT01375764

Public ClinicalTrials.gov record NCT01375764. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter Study to Evaluate Tolerability and Efficacy of AMG 145 on LDL-C, Compared With Ezetimibe, in Hypercholesterolemic Subjects Unable to Tolerate an Effective Dose of a HMG-CoA Reductase Inhibitor

Study identification

NCT ID
NCT01375764
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
160 participants

Conditions and interventions

Conditions

Interventions

  • Evolocumab Biological
  • Ezetimibe Drug
  • Placebo to Evolocumab Other

Biological · Drug · Other

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 27, 2011
Primary completion
May 7, 2012
Completion
May 7, 2012
Last update posted
Nov 6, 2022

2011 – 2012

United States locations

U.S. sites
16
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
Research Site Anaheim California 92801
Research Site Mission Viejo California 92691
Research Site Westlake Village California 91361
Research Site Atlanta Georgia 30338
Research Site Atlanta Georgia 30342
Research Site Savannah Georgia 31406
Research Site Auburn Maine 04210
Research Site Chevy Chase Maryland 20815
Research Site Butte Montana 59701
Research Site Henderson Nevada 89052
Research Site Las Vegas Nevada 89117
Research Site New York New York 10029
Research Site Raleigh North Carolina 27609
Research Site Akron Ohio 44311
Research Site Cincinnati Ohio 45212
Research Site Bristol Tennessee 37620

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01375764, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 6, 2022 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01375764 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →