Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain
Public ClinicalTrials.gov record NCT01384292. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of NKTR-118 in Relieving Opioid-Induced Constipation (OIC) in Patients With Cancer-Related Pain
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the effect of NKTR-118 with placebo in the treatment of opioid-induced constipation (OIC) in patients with cancer-related pain, including those patients that have inadequate response to laxative therapy (LIR). The study consists of 2 parts; A initial 4-week treatment period (part A) and then a 12 week extension with active treatment (part B).
Study identification
- NCT ID
- NCT01384292
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 14 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2011 (Type not available)
- Primary completion
- Sep 2012 (Actual)
- Completion
- Sep 2012 (Actual)
- Last update posted
- Jun 1, 2015
2011 – 2012
United States locations
- U.S. sites
- 81
- U.S. states
- 31
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Huntsville | Alabama | — | — |
| Research Site | Casa Grande | Arizona | — | — |
| Research Site | Phoenix | Arizona | — | — |
| Research Site | Tucson | Arizona | — | — |
| Research Site | Fort Smith | Arkansas | — | — |
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| Research Site | Baypines | Florida | — | — |
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| Research Site | Celebration | Florida | — | — |
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| Research Site | Miami Lakes | Florida | — | — |
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| Research Site | Plantation | Florida | — | — |
| Research Site | Tavares | Florida | — | — |
| Research Site | Albany | Georgia | — | — |
| Research Site | Marietta | Georgia | — | — |
| Research Site | Riverdale | Georgia | — | — |
| Research Site | Roswell | Georgia | — | — |
| Research Site | Honolulu | Hawaii | — | — |
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| Research Site | Anderson | Indiana | — | — |
| Research Site | Evansville | Indiana | — | — |
| Research Site | Owensboro | Kentucky | — | — |
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| Research Site | Elkridge | Maryland | — | — |
| Research Site | Hollywood | Maryland | — | — |
| Research Site | Boston | Massachusetts | — | — |
| Research Site | Fairhaven | Massachusetts | — | — |
| Research Site | Detroit | Michigan | — | — |
| Research Site | Kalamazoo | Michigan | — | — |
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| Research Site | Toms River | New Jersey | — | — |
| Research Site | Voorhees Township | New Jersey | — | — |
| Research Site | Great Neck | New York | — | — |
| Research Site | Syracuse | New York | — | — |
| Research Site | Chapel Hill | North Carolina | — | — |
| Research Site | Flat Rock | North Carolina | — | — |
| Research Site | Morrisville | North Carolina | — | — |
| Research Site | Wilmington | North Carolina | — | — |
| Research Site | Winston-Salem | North Carolina | — | — |
| Research Site | Bismarck | North Dakota | — | — |
| Research Site | Akron | Ohio | — | — |
| Research Site | Beavercreek | Ohio | — | — |
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| Research Site | Middleton | Ohio | — | — |
| Research Site | Danville | Pennsylvania | — | — |
| Research Site | East Providence | Rhode Island | — | — |
| Research Site | Charleston | South Carolina | — | — |
| Research Site | Chattanooga | Tennessee | — | — |
| Research Site | Beaumont | Texas | — | — |
| Research Site | Bellaire | Texas | — | — |
| Research Site | Corpus Christi | Texas | — | — |
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| Research Site | Houston | Texas | — | — |
| Research Site | Lubbock | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Sugarland | Texas | — | — |
| Research Site | Fairfax | Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 59 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01384292, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 1, 2015 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01384292 live on ClinicalTrials.gov.