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Completed Phase 2 Interventional Results available

Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis

ClinicalTrials.gov ID: NCT01385748

Public ClinicalTrials.gov record NCT01385748. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multi-center, Randomised, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Clonidine Lauriad® 50 μg and 100 μg Mucoadhesive Buccal Tablet (MBT) Applied Once Daily to Those of Placebo in the Prevention and Treatment of Chemoradiation Therapy Induced Oral Mucositis in Patients With Head and Neck Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of Clonidine Lauriad® to treat chemoradiation therapy induced severe oral mucositis in patients with head and neck cancer.

Study identification

NCT ID
NCT01385748
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Valerio Therapeutics
Industry
Enrollment
183 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2010
Primary completion
Sep 30, 2014
Completion
Nov 30, 2014
Last update posted
Nov 27, 2017

2010 – 2014

United States locations

U.S. sites
19
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
21st Century Oncology of Arizona Sun City Arizona 85251
Compassionate Cancer Care Medical Group Corona California 92879
City of Hope Duarte California 91010
California Cancer Associates for Researche and Excellence Fresno California 93720
Compassionate Cancer Care Medical Group Riverside California 92501
Central Coast Medical Oncology Corp. Santa Maria California 93454
Centura Health Research Center Denver Colorado 80210
University of Connectcut Health Center Farmington Connecticut 06030
AMPM Research Clinic Miami Florida 33145
Barbara Ann Karmonos Cancer Hospital Detroit Michigan 48201
Washington University School of medecine St Louis Missouri 63110
Billings Clinic Montana Billings Montana 59101
Winthrop University Hospital Mineola New York 11501
Montefiore Medical Center The Bronx New York 10467
Carolinas Medical Center- Carolinas Health Care System Charlotte North Carolina 28203
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Penn State Hershey Cancer Institut Hershey Pennsylvania 17033
Vanderbilt Ingram Cancer Center Nashville Tennessee 37232
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01385748, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 27, 2017 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01385748 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →