Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)

ClinicalTrials.gov ID: NCT01392092

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Official title

Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

N-acetylcysteine (NAC) is a medication that the Food and Drug Administration (FDA) has approved for several medical uses, such as dissolving mucus in patients with breathing problems, treating overdose from acetaminophen (Tylenol), and protecting the kidneys from toxic substances. Some recent studies suggest that NAC could be useful in the treatment of other disorders including addictions. One purpose of this study is to determine whether NAC alters the level of brain glutamate (a chemical that excites brain cells). The other main purpose is to determine whether NAC affects how much cocaine people use.

Study identification

NCT ID: NCT01392092
Recruitment status: Completed
Study type: Observational
Phase: Not listed
Lead sponsor: Wayne State University; Other
Enrollment: 16 participants

Conditions and interventions

Conditions

Interventions

Not listed

Eligibility (public fields only)

Age range: 18 Years to 55 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 2011 (Type not available)
Primary completion: Jun 2017 (Actual)
Completion: Jun 2017 (Actual)
Last update posted: Apr 5, 2018

2011 – 2017

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
Wayne State University	Detroit	Michigan	48201	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT01392092, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 5, 2018 · Synced Nov 14, 2026