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Completed Phase 2 Interventional

A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT01397578

Public ClinicalTrials.gov record NCT01397578. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter, Phase II Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase II, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the effects of MABT5102A on brain amyloid burden (as assessed by amyloid PET imaging) and other biomarkers in patients with mild to moderate Alzheimer's disease.

Study identification

NCT ID
NCT01397578
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
91 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2011 (Actual)
Primary completion
Apr 30, 2014 (Actual)
Completion
Apr 30, 2014 (Actual)
Last update posted
Jul 12, 2017

2011 – 2014

United States locations

U.S. sites
22
U.S. states
12
U.S. cities
21
Facility City State ZIP Site status
Banner Alzheimer's Institute Phoenix Arizona 85020 —
Banner Sun Health Research Insitute Sun City Arizona 85351 —
NNS Clinical Research LLC Tucson Arizona 85704 —
Margolin Brain Institute Fresno California 93720 —
University of California Los Angeles (UCLA) Los Angeles California 90095 —
Pacific Neuroscience Med Grp Oxnard California 93030 —
Stanford Univ Medical Center Palo Alto California 94304 —
Redwood Regional Medical Group Santa Rosa California 95403 —
Internal Med Assoc of Lee Cty Fort Myers Florida 33912 —
Neuropsychiatric Research; Center of Southwest Florida Fort Myers Florida 33912 —
MD Clinical Hallandale Florida 33009 —
Compass Research Orlando Florida 32806 —
Dekalb Neurology Associates Decatur Georgia 30033 —
Alexian Brothers Neurosci Inst Elk Grove Village Illinois 60007 —
Hattiesburg Clinic Hattiesburg Mississippi 39401 —
Cleveland Clinic Lou Ruvo; Center for Brain Research Las Vegas Nevada 89106 —
Memory Enhancement Center of America, Inc. Eatontown New Jersey 07724 —
Litwin Zucker Research Ctr.; Feinstein Inst. Med. Rsch. Manhasset New York 11030 —
Neurology & Neuroscience Ctr of Ohio Toledo Ohio 43623 —
The Clinical Trial Center, LLC Jenkintown Pennsylvania 19046 —
Rhode Island Mood & Memory Research Institute East Providence Rhode Island 02914 —
Butler Hospital Providence Rhode Island 02906 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01397578, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 12, 2017 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01397578 live on ClinicalTrials.gov.

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