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Completed Phase 3 Interventional Results available

Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)

ClinicalTrials.gov ID: NCT01404312

Public ClinicalTrials.gov record NCT01404312. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection

Study identification

NCT ID
NCT01404312
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
3,000 participants

Conditions and interventions

Interventions

  • Rifapentine (RPT) Drug
  • Isoniazid (INH) Drug
  • Pyridoxine (Vitamin B6) Dietary Supplement

Drug · Dietary Supplement

Eligibility (public fields only)

Age range
13 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 22, 2012
Primary completion
Nov 13, 2017
Completion
Nov 13, 2017
Last update posted
Nov 3, 2021

2012 – 2017

United States locations

U.S. sites
21
U.S. states
11
U.S. cities
20
Facility City State ZIP Site status
University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program La Jolla California 92093-0672
University of Southern California CRS Los Angeles California 90033-1079
UCSD Antiviral Research Center CRS San Diego California 92103
Ucsf Hiv/Aids Crs San Francisco California 94110
Harbor-UCLA CRS Torrance California 90502
University of Colorado Hospital CRS Aurora Colorado 80045
Denver Public Health CRS Denver Colorado 80204
The University of Miami AIDS Clinical Research Unit (ACRU) CRS Miami Florida 33136
Northwestern University CRS Chicago Illinois 60611
Boston Medical Center CRS Boston Massachusetts 02118
Henry Ford Hosp. CRS Detroit Michigan 48202
Cooper Univ. Hosp. CRS Camden New Jersey 08103
New Jersey Medical School Clinical Research Center CRS Newark New Jersey 07103
Nyu Ny Nichd Crs New York New York 10016
Columbia P&S CRS New York New York 10032-3732
Bronx-Lebanon Hospital Center NICHD CRS The Bronx New York 10457
Chapel Hill CRS Chapel Hill North Carolina 27599
Duke University Medical Center CRS Durham North Carolina 27710
Trinity Health and Wellness Center CRS Dallas Texas 75208
Houston AIDS Research Team CRS Houston Texas 77030
University of Washington AIDS CRS Seattle Washington 98104-9929

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01404312, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 3, 2021 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01404312 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →