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Not listed Phase 2 Interventional

A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients

ClinicalTrials.gov ID: NCT01408602

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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT01408602. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

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Official title

A 24-week, Phase 2, Double-blind, Placebo-controlled, Randomized Study to Assess the Safety and Efficacy of 2 Doses of MRC375 in Patients With Moderate to Severe Rheumatoid Arthritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will treat moderate to severe rheumatoid arthritis with MRC375 (either 75 mg 3 times a day, 150 mg 3 times a day or placebo 3 times a day)in patients 18 years of age or older that can be currently on low doses of methotrexate or can stop treatment of current RA medications to enter the study. Safety of MRC375 will also be evaluated. There are up to 8 clinic visits over 24 weeks.

Study identification

NCT ID
NCT01408602
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Molecular Research Center, Inc.
Industry
Enrollment
300 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2011 (Type not available)
Primary completion
Jul 2014 (Estimated)
Completion
Jul 2014 (Estimated)
Last update posted
May 12, 2014

2011 – 2014

United States locations

U.S. sites
19
U.S. states
11
U.S. cities
19
Facility City State ZIP Site status
Mobile Diagnostic Center Rheumatology Mobile Alabama 36608 —
Valerius Medical Group Long Beach California 90806 —
Trial Concierge/Pacific Clinical Studies Los Alamitos California 90720 —
Axis Clinical Trials Los Angeles California 90036 —
Riverside Clinical Research Edgewater Florida 32132 —
Global Clinical Professionals Miami Florida 33156 —
The Arthritis Center Palm Harbor Florida 34684 —
Lakeview Medical Research Summerfield Florida 34491 —
Analan Clinical Research Lenexa Kansas 66219 —
Trial Concierge Owensboro Kentucky 42303 —
Quality Clinical Research, Inc. Omaha Nebraska 68114 —
Advanced BioMedical Research of America Las Vegas Nevada 89123 —
Arthritis Center of Reno Reno Nevada 89502 —
PMG Research of Salisbury Salisbury North Carolina 28144 —
Providence Health Partners Dayton Ohio 45439 —
Paramount Medical Research & Consulting, LLC Middleburg Heights Ohio 44130 —
The Center for Excellence in Aging and Geriatric Health Williamsburg Virginia 23185 —
Apex Clinical Research Kennewick Washington 99336 —
South Puget Sound Clinical Research Center Olympia Washington 98502 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01408602, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 12, 2014 · Synced Nov 12, 2026

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