A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients
Public ClinicalTrials.gov record NCT01408602. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 24-week, Phase 2, Double-blind, Placebo-controlled, Randomized Study to Assess the Safety and Efficacy of 2 Doses of MRC375 in Patients With Moderate to Severe Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will treat moderate to severe rheumatoid arthritis with MRC375 (either 75 mg 3 times a day, 150 mg 3 times a day or placebo 3 times a day)in patients 18 years of age or older that can be currently on low doses of methotrexate or can stop treatment of current RA medications to enter the study. Safety of MRC375 will also be evaluated. There are up to 8 clinic visits over 24 weeks.
Study identification
- NCT ID
- NCT01408602
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2011
- Primary completion
- Jun 30, 2014
- Completion
- Jun 30, 2014
- Last update posted
- May 11, 2014
2011 – 2014
United States locations
- U.S. sites
- 19
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mobile Diagnostic Center Rheumatology | Mobile | Alabama | 36608 | — |
| Valerius Medical Group | Long Beach | California | 90806 | — |
| Trial Concierge/Pacific Clinical Studies | Los Alamitos | California | 90720 | — |
| Axis Clinical Trials | Los Angeles | California | 90036 | — |
| Riverside Clinical Research | Edgewater | Florida | 32132 | — |
| Global Clinical Professionals | Miami | Florida | 33156 | — |
| The Arthritis Center | Palm Harbor | Florida | 34684 | — |
| Lakeview Medical Research | Summerfield | Florida | 34491 | — |
| Analan Clinical Research | Lenexa | Kansas | 66219 | — |
| Trial Concierge | Owensboro | Kentucky | 42303 | — |
| Quality Clinical Research, Inc. | Omaha | Nebraska | 68114 | — |
| Advanced BioMedical Research of America | Las Vegas | Nevada | 89123 | — |
| Arthritis Center of Reno | Reno | Nevada | 89502 | — |
| PMG Research of Salisbury | Salisbury | North Carolina | 28144 | — |
| Providence Health Partners | Dayton | Ohio | 45439 | — |
| Paramount Medical Research & Consulting, LLC | Middleburg Heights | Ohio | 44130 | — |
| The Center for Excellence in Aging and Geriatric Health | Williamsburg | Virginia | 23185 | — |
| Apex Clinical Research | Kennewick | Washington | 99336 | — |
| South Puget Sound Clinical Research Center | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01408602, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2014 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01408602 live on ClinicalTrials.gov.