A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis
Public ClinicalTrials.gov record NCT01416181. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy of Natalizumab on Reducing Disability Progression in Subjects With Secondary Progressive Multiple Sclerosis, With Optional Open-Label Extension
Study identification
- NCT ID
- NCT01416181
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Biogen
- Industry
- Enrollment
- 889 participants
Conditions and interventions
Conditions
Interventions
- natalizumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 58 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 12, 2011
- Primary completion
- Jul 27, 2015
- Completion
- Apr 12, 2016
- Last update posted
- Sep 10, 2017
2011 – 2016
United States locations
- U.S. sites
- 35
- U.S. states
- 22
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85013 | — |
| Research Site | Tucson | Arizona | 85741 | — |
| Research Site | Fullerton | California | 92835 | — |
| Research Site | Los Angeles | California | 90027 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | Tampa | Florida | 33612 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Lake Barrington | Illinois | 60010 | — |
| Research Site | Peoria | Illinois | 61606 | — |
| Research Site | Indianapolis | Indiana | 46202 | — |
| Research Site | Indianapolis | Indiana | 46256 | — |
| Research Site | Kansas City | Kansas | 66160 | — |
| Research Site | Lexington | Kentucky | 40513 | — |
| Research Site | Lexington | Kentucky | 40536 | — |
| Research Site | Baltimore | Maryland | 21287 | — |
| Research Site | Burlington | Massachusetts | 01805 | — |
| Research Site | Omaha | Nebraska | 68198 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Teaneck | New Jersey | 07666 | — |
| Research Site | Latham | New York | 12110 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Advance | North Carolina | 27006 | — |
| Research Site | Charlotte | North Carolina | 28207 | — |
| Research Site | Raleigh | North Carolina | 27607 | — |
| Research Site | Akron | Ohio | 44320 | — |
| Research Site | Uniontown | Ohio | 44685 | — |
| Research Site | Oklahoma City | Oklahoma | 73104 | — |
| Research Site | Clackamas | Oregon | 97015 | — |
| Research Site | Portland | Oregon | 97225 | — |
| Research Site | Portland | Oregon | 97239 | — |
| Research Site | Nashville | Tennessee | 37215 | — |
| Research Site | Charlottesville | Virginia | 22903 | — |
| Research Site | Seattle | Washington | 98101 | — |
| Research Site | Green Bay | Wisconsin | 54311 | — |
| Research Site | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 126 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01416181, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2017 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01416181 live on ClinicalTrials.gov.