Cognitive REmediation After Trauma Exposure Trial = CREATE Trial
Public ClinicalTrials.gov record NCT01416948. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized Controlled Trial of Galantamine, Methylphenidate, and Placebo for the Treatment of Cognitive Symptoms in Patients With Traumatic Brain Injury (TBI) and/or Posttraumatic Stress Disorder (PTSD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy of methylphenidate and galantamine in the treatment of persistent cognitive symptoms associated with posttraumatic stress disorder (PTSD) and/or traumatic brain injury (TBI).
Study identification
- NCT ID
- NCT01416948
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
- Other
- Enrollment
- 32 participants
Conditions and interventions
Interventions
- Methylphenidate Hydrochloride 20 mg Drug
- Placebo Capsule Drug
- Galantamine 12 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2011
- Primary completion
- Feb 28, 2013
- Completion
- Feb 28, 2013
- Last update posted
- Apr 25, 2013
2011 – 2013
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| VA San Diego Healthcare System | San Diego | California | 92161 | — |
| Spaulding Rehabilitation Hospital | Boston | Massachusetts | 02114 | — |
| Manchester VA Medical Center | Manchester | New Hampshire | 03104 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Ralph H. Johnson VA Medical Center | Charleston | South Carolina | 29401 | — |
| White River Junction VA Medical Center | White River Junction | Vermont | 05009 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01416948, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 25, 2013 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01416948 live on ClinicalTrials.gov.