A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy
Public ClinicalTrials.gov record NCT01419197. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Multicenter, Two Arm, Open-label Trial to Evaluate the Efficacy of Trastuzumab Emtansine Compared With Treatment of Physician's Choice in Patients With HER2-positive Metastatic Breast Cancer Who Have Received at Least Two Prior Regimens of HER2 Directed Therapy
Study identification
- NCT ID
- NCT01419197
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 602 participants
Conditions and interventions
Conditions
Interventions
- Trastuzumab emtansine Drug
- Treatment of physician's choice Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2011
- Primary completion
- Jan 31, 2013
- Completion
- Jul 31, 2015
- Last update posted
- Oct 11, 2016
2011 – 2015
United States locations
- U.S. sites
- 59
- U.S. states
- 32
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Tucson | Arizona | 85704 | — |
| Not listed | Hot Springs | Arkansas | 71913 | — |
| Not listed | Hayward | California | 94545 | — |
| Not listed | Highland | California | 92346 | — |
| Not listed | Oakland | California | 94611 | — |
| Not listed | Roseville | California | 95661 | — |
| Not listed | Sacramento | California | 95825 | — |
| Not listed | San Diego | California | 92108 | — |
| Not listed | San Francisco | California | 94115 | — |
| Not listed | San Jose | California | 95119 | — |
| Not listed | Santa Clara | California | 95051 | — |
| Not listed | South San Francisco | California | 94080 | — |
| Not listed | Stockton | California | 95204 | — |
| Not listed | Vallejo | California | 94589 | — |
| Not listed | Walnut Creek | California | 94596 | — |
| Not listed | West Hollywood | California | 90048 | — |
| Not listed | Denver | Colorado | 80220 | — |
| Not listed | Trumbull | Connecticut | 06611 | — |
| Not listed | Newark | Delaware | 19713 | — |
| Not listed | Washington D.C. | District of Columbia | 20010 | — |
| Not listed | Coral Springs | Florida | 33065 | — |
| Not listed | Deerfield Beach | Florida | 33442 | — |
| Not listed | Fort Myers | Florida | 33905 | — |
| Not listed | Jacksonville | Florida | 32256 | — |
| Not listed | Plantation | Florida | 33324 | — |
| Not listed | Marietta | Georgia | 30060 | — |
| Not listed | Post Falls | Idaho | 83854 | — |
| Not listed | Chicago | Illinois | 60612 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Maywood | Illinois | 60153 | — |
| Not listed | Fort Wayne | Indiana | 46815 | — |
| Not listed | Sioux City | Iowa | 51101 | — |
| Not listed | Wichita | Kansas | 67214-3728 | — |
| Not listed | Scarborough | Maine | 04074 | — |
| Not listed | Bethesda | Maryland | 20817 | — |
| Not listed | Columbia | Maryland | 21044 | — |
| Not listed | Boston | Massachusetts | 02115 | — |
| Not listed | Boston | Massachusetts | 02130 | — |
| Not listed | Boston | Massachusetts | 02215 | — |
| Not listed | Detroit | Michigan | 48201 | — |
| Not listed | Minneapolis | Minnesota | 55455 | — |
| Not listed | St Louis | Missouri | 63141 | — |
| Not listed | Omaha | Nebraska | 68114 | — |
| Not listed | New Brunswick | New Jersey | 08901 | — |
| Not listed | Lake Success | New York | 11042 | — |
| Not listed | The Bronx | New York | 10467 | — |
| Not listed | Charlotte | North Carolina | 28203 | — |
| Not listed | Columbus | Ohio | 43219 | — |
| Not listed | Portland | Oregon | 97210 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Charleston | South Carolina | 29414 | — |
| Not listed | Chattanooga | Tennessee | 37404 | — |
| Not listed | Nashville | Tennessee | 37203 | — |
| Not listed | Nashville | Tennessee | 37232 | — |
| Not listed | Dallas | Texas | 75246 | — |
| Not listed | Fort Worth | Texas | 76104 | — |
| Not listed | San Antonio | Texas | 78229 | — |
| Not listed | Richmond | Virginia | 23230 | — |
| Not listed | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 125 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01419197, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 11, 2016 · Synced May 13, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01419197 live on ClinicalTrials.gov.