ClinicalTrials.gov record
VA Augmentation and Switching Treatments for Improving Depression Outcomes
ClinicalTrials.gov ID: NCT01421342
Public ClinicalTrials.gov record NCT01421342. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 7, 2026, 2:37 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CSP #576 - VA Augmentation and Switching Treatments for Improving Depression Outcomes (VAST-D)
Study identification
- NCT ID
- NCT01421342
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- VA Office of Research and Development
- Federal
- Enrollment
- 1,522 participants
Conditions and interventions
Conditions
Interventions
- Augmenting: Antidepressant + Aripiprazole Drug
- Augmenting: Antidepressant + Bupropion-SR Drug
- Switching: Bupropion-SR Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2012
- Primary completion
- Jul 31, 2015
- Completion
- May 31, 2016
- Last update posted
- May 28, 2018
2012 – 2016
United States locations
- U.S. sites
- 35
- U.S. states
- 24
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tuscaloosa VA Medical Center, Tuscaloosa, AL | Tuscaloosa | Alabama | 35404 | — |
| Phoenix VA Health Care System, Phoenix, AZ | Phoenix | Arizona | 85012 | — |
| Southern Arizona VA Health Care System, Tucson | Tucson | Arizona | 85723 | — |
| VA Loma Linda Healthcare System, Loma Linda, CA | Loma Linda | California | 92357 | — |
| VA Long Beach Healthcare System, Long Beach, CA | Long Beach | California | 90822 | — |
| VA Palo Alto Health Care System, Palo Alto, CA | Palo Alto | California | 94304-1290 | — |
| VA San Diego Healthcare System, San Diego, CA | San Diego | California | 92161 | — |
| San Francisco VA Medical Center, San Francisco, CA | San Francisco | California | 94121 | — |
| VA Eastern Colorado Health Care System, Denver, CO | Denver | Colorado | 80220 | — |
| VA Connecticut Healthcare System West Haven Campus, West Haven, CT | West Haven | Connecticut | 06516 | — |
| Washington DC VA Medical Center, Washington, DC | Washington D.C. | District of Columbia | 20422 | — |
| Miami VA Healthcare System, Miami, FL | Miami | Florida | 33125 | — |
| James A. Haley Veterans' Hospital, Tampa, FL | Tampa | Florida | 33612 | — |
| Atlanta VA Medical and Rehab Center, Decatur, GA | Decatur | Georgia | 30033 | — |
| Edward Hines Jr. VA Hospital, Hines, IL | Hines | Illinois | 60141-5000 | — |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Indianapolis | Indiana | 46202-2884 | — |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD | Baltimore | Maryland | 21201 | — |
| Minneapolis VA Health Care System, Minneapolis, MN | Minneapolis | Minnesota | 55417 | — |
| Kansas City VA Medical Center, Kansas City, MO | Kansas City | Missouri | 64128 | — |
| St. Louis VA Medical Center John Cochran Division, St. Louis, MO | St Louis | Missouri | 63106 | — |
| Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE | Omaha | Nebraska | 68105-1873 | — |
| New Mexico VA Health Care System, Albuquerque, NM | Albuquerque | New Mexico | 87108-5153 | — |
| Asheville VA Medical Center, Asheville, NC | Asheville | North Carolina | 28805 | — |
| Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC | Salisbury | North Carolina | 28144 | — |
| Cincinnati VA Medical Center, Cincinnati, OH | Cincinnati | Ohio | 45220 | — |
| Louis Stokes VA Medical Center, Cleveland, OH | Cleveland | Ohio | 44106 | — |
| Philadelphia VA Medical Center, Philadelphia, PA | Philadelphia | Pennsylvania | 19104 | — |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Pittsburgh | Pennsylvania | 15240 | — |
| Memphis VA Medical Center, Memphis, TN | Memphis | Tennessee | 38104 | — |
| Central Texas Veterans Health Care System, Temple, TX | Temple | Texas | 76504 | — |
| Salem VA Medical Center, Salem, VA | Salem | Virginia | 24153 | — |
| VA Puget Sound Health Care System American Lake Division, Tacoma, WA | Tacoma | Washington | 98493 | — |
| Clarksburg Louis A. Johnson VA Medical Center, Clarksburg, WV | Clarksburg | West Virginia | 26301 | — |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Madison | Wisconsin | 53705 | — |
| Clement J. Zablocki VA Medical Center, Milwaukee, WI | Milwaukee | Wisconsin | 53295-1000 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01421342, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2018 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01421342 live on ClinicalTrials.gov.