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Completed Phase 2 Interventional Results available

A Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer

ClinicalTrials.gov ID: NCT01421472

Public ClinicalTrials.gov record NCT01421472. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:07 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Phase 2 Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To demonstrate whether addition of MM-121 to paclitaxel is more effective than treatment with paclitaxel alone, when administered as part of the neoadjuvant treatment in Her2 negative locally advanced operable breast cancer patients.

Study identification

NCT ID
NCT01421472
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Merrimack Pharmaceuticals
Industry
Enrollment
196 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2011 (Type not available)
Primary completion
Dec 2013 (Actual)
Completion
Jun 2014 (Actual)
Last update posted
May 3, 2016

2011 – 2014

United States locations

U.S. sites
38
U.S. states
16
U.S. cities
35
Facility City State ZIP Site status
Universito of Birmingham atAlabama Birmingham Alabama 35294 —
Arizona Oncology Associates Tucson Arizona 85704 —
Arizona Oncology Associates Tuscon Arizona 85715 —
Marin Cancer Center Greenbrae California 94904 —
PMK Medical Group Oxnard California 93030 —
Wilshire Oncology Medical Group Rancho Cucamonga California 91730 —
Florida Cancer Research Institute Plantation Florida 33324 —
Piedmont Healthcare Altanta Georgia 30214 —
Piedmont Fayette Hospital Fayetteville Georgia 30214 —
Georgia Cancer Specialists Marietta Georgia 30341 —
University Of Chicago Chicago Illinois 60637 —
Illinois Cancer Specialists Niles Illinois 60714 —
Dana-Farber Cancer Institute Boston Massachusetts 02114 —
Dana Farber Cancer Institute Boston Massachusetts 02215 —
Beaumont Health Systems Royal Oak Michigan 48073 —
Comprehensive Cancer Centers of Nevada Henderson Nevada 89074 —
Cooper Cancer Institute Voorhees Township New Jersey 08043 —
University of New Mexico Cancer Center Albuquerque New Mexico 87106 —
Memorial Medical Center Las Cruces New Mexico 88011 —
Northwest Cancer Specialists Portland Oregon 97225 —
Cancer Center of the Carolinas Greenville South Carolina 29605 —
Texas Oncology - Amarillo Amarillo Texas 79106 —
Texas Oncology-Austin Central Austin Texas 78731 —
Texas Oncology - Bedford Bedford Texas 76022 —
Texas Oncology - Medical City Dallas Texas 75230 —
Texas Oncology - Dallas Dallas Texas 75231 —
Texas Oncology - Baylor Charles A Sammons Cancer Center Dallas Texas 75246 —
Texas Oncology -El Paso El Paso Texas 79902 —
Texas Oncology - Garland Garland Texas 75042 —
Texas Oncology - Memorial City Houston Texas 77024 —
Texas Oncology - Lewisville Lewisville Texas 75067 —
Texas Oncology - McAllen McAllen Texas 78503 —
Texas Oncology Plano East Plano Texas 75075-7787 —
Cancer Care Centers of South Texas San Antonio Texas 78217 —
Texas Oncology - Tyler Tyler Texas 75702 —
Virginia Oncology Associates Norfolk Virginia 23502 —
Puget Sound Cancer Center Seattle Washington 98133 —
Yakima Valley Memorial Hospital Yakima Washington 98902 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01421472, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 3, 2016 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01421472 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →